Allele Dmel\CG6194^P0997

General Information
Symbol	Dmel\CG6194^P0997	Species	D. melanogaster
Name		FlyBase ID	FBal0152691
Feature type	allele	Associated gene	Dmel\CG6194

Allele class
Mutagen	P-element activity
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	P-element activity (Thumm and Kadowaki, 2001)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	P{lacW}CG6194^P0997 (Thumm and Kadowaki, 2001, Scott et al., 2004)
Cytology
Phenotypic Data
Phenotypic Class
	fertile (Thumm and Kadowaki, 2001) viable (Scott et al., 2004, Thumm and Kadowaki, 2001)
Phenotype Manifest In

Detailed Description
	Statement Reference No disruption of autophagy. (Scott et al., 2004)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement Reference CG6194[+]/CG6194^P0997 is an enhancer of visible \| dominant phenotype of Dl^X (Thumm and Kadowaki, 2001) CG6194^P0997/CG6194^P0997 is an enhancer of visible phenotype of dx¹ (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001) CG6194^P0997/CG6194^P0997 is an enhancer of visible phenotype of N^nd-3 (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001) CG6194^P0997/CG6194^P0997 is an enhancer of visible phenotype of sno^71e3 (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001)
Suppressor of
Statement Reference CG6194[+]/CG6194^P0997 is a suppressor of visible \| dominant phenotype of H^E31 (Thumm and Kadowaki, 2001) CG6194^P0997/CG6194^P0997 is a suppressor of visible phenotype of N^Ax-1 (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001)
Other
Statement Reference CG6194[+]/CG6194^P0997, Ser^Bd-1 has visible phenotype (Thumm and Kadowaki, 2001) CG6194^P0997, Ser^Bd-1 has visible phenotype (Thumm and Kadowaki, 2001) CG6194^P0997, vg¹ has visible phenotype (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001)
Phenotype Manifest In
Enhancer of
Statement Reference CG6194[+]/CG6194^P0997 is an enhancer of wing vein L2 phenotype of Dl^X (Thumm and Kadowaki, 2001) CG6194[+]/CG6194^P0997 is an enhancer of wing vein phenotype of Dl^X (Thumm and Kadowaki, 2001) CG6194^P0997/CG6194^P0997 is an enhancer of ommatidium phenotype of sno^71e3 (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001) CG6194^P0997/CG6194^P0997 is an enhancer of wing margin phenotype of N^nd-3 (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001) CG6194^P0997/CG6194^P0997 is an enhancer of wing phenotype of sno^71e3 (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001) CG6194^P0997/CG6194^P0997 is an enhancer of wing vein phenotype of dx¹ (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001) CG6194^P0997/CG6194^P0997 is an enhancer of wing vein phenotype of sno^71e3 (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001) CG6194^P0997 is an enhancer of wing phenotype of ct^53d (Thumm and Kadowaki, 2001)
NOT Enhancer of
Statement Reference CG6194^P0997/CG6194^P0997 is a non-enhancer of wing phenotype of arm⁴ (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001) CG6194^P0997/CG6194^P0997 is a non-enhancer of wing phenotype of sgg³² (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001) CG6194^P0997/CG6194^P0997 is a non-enhancer of wing phenotype of wg^l-17 (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001)
Suppressor of
Statement Reference CG6194[+]/CG6194^P0997 is a suppressor of wing vein L5 phenotype of H^E31 (Thumm and Kadowaki, 2001) CG6194^P0997/CG6194^P0997 is a suppressor of wing vein phenotype of N^Ax-1 (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001)
NOT Suppressor of
Statement Reference CG6194^P0997/CG6194^P0997 is a non-suppressor of wing phenotype of arm⁴ (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001) CG6194^P0997/CG6194^P0997 is a non-suppressor of wing phenotype of sgg³² (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001) CG6194^P0997/CG6194^P0997 is a non-suppressor of wing phenotype of wg^l-17 (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001)
Other
Statement Reference CG6194[+]/CG6194^P0997, Ser^Bd-1 has wing phenotype (Thumm and Kadowaki, 2001) CG6194^P0997, dx¹ has wing margin phenotype (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001) CG6194^P0997, Ser^Bd-1 has wing phenotype (Thumm and Kadowaki, 2001) CG6194^P0997, vg¹ has wing margin phenotype (Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001, Thumm and Kadowaki, 2001)
Additional Comments
Genetic Interactions
Statement Reference The wing notching phenotype seen in ct^53d adults is enhanced in a dose dependent manner by CG6194^P0997. CG6194^P0997/CG6194^P0997 enhances the loss of wing margin seen in N^nd-3/Y flies. CG6194^P0997/CG6194^P0997 suppresses the loss of wing vein seen in N^Ax-1/Y flies. CG6194^P0997/CG6194^P0997 enhances wing vein thickenings and wing margin loss in dx¹/Y flies. The shortening of wing vein L5 seen in H^E31/+ flies is suppressed by CG6194^P0997/+. Ser^Bd-1 CG6194^P0997 double heterozygotes show notching of the wing. The wing vein thickenings of L2 and terminal deltas seen in Dl^X/+ flies is enhanced by CG6194^P0997/+. vg¹/+ CG6194^P0997/CG6194^P0997 flies show loss of wing margin tissue. The notching of the wing and wing vein thickening seen in sno^71e3/Y males is enhanced by CG6194^P0997/CG6194^P0997. The sno^71e3/Y rough eye phenotype is also enhanced. (Thumm and Kadowaki, 2001)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 1 )
Bloomington	36340 y¹ w^*; P{lacW}CG6194^P0997
Notes on Origin
Discoverer
	Selected as: a modifier of the ct^53d wing phenotype. (Thumm and Kadowaki, 2001)
Comments
	CG6194 mRNA is absent in CG6194^P0997 homozygous embryos (but present in wild-type embryos). Excision of the P{lacW} element can revert the CG6194^P0997 phenotype of enhancing ct^53d. (Thumm and Kadowaki, 2001)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG6194^P0997 P0997 (Thumm and Kadowaki, 2001)
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Thumm and Kadowaki, 2001, Mol. Genet. Genomics 266(4): 657--663 The loss of Drosophila APG4/AUT2 function modifies the phenotypes of cut and Notch signaling pathway mutants. [FBrf0145130]
Supplementary material	Scott et al., 2004, Dev. Cell 7(2): Supplementary material. [FBrf0183440]

Allele Dmel\CG6194P0997

Allele Dmel\CG6194^P0997