FlyBase Allele Report: Dmel\Ant2[G0126]

General Information

Symbol

Dmel\Ant2^G0126

Species

D. melanogaster

Name

FlyBase ID

FBal0152784

Feature type

allele

Associated gene

Dmel\Ant2

Associated Insertion(s)

P{lacW}Ant2^G0126

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Schäfer et al., 1999.6.15, Schäfer et al., 1999.8.12)

Progenitor genotype

Associated Insertion(s)

P{lacW}Ant2^G0126

Cytology

Description

The P{lacW} insertion maps within both Ant2 and sesB (transcription units with non-overlapping ORFs which share untranslated sequences).

(FlyBase, 1996-)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:10,784,431..10,784,854 [-]

(Peter et al., 2002, Schäfer et al., 1999.6.15, Schäfer et al., 1999.8.12, FlyBase, 1996-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

AJ426849

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Schäfer et al., 1999.8.12)

lethal - all die before end of P-stage | recessive

(Peter et al., 2002)

partially lethal - majority die | recessive

(Schäfer et al., 1999.6.15)

some die during pharate adult stage | recessive

(Peter et al., 2002)

Phenotype Manifest In

Detailed Description

Statement

Reference

FlyBase curator comment: the P{lacW} insertion results in homozygous lethality, but since the insertion is within both the Ant2 and sesB transcription units, it is unclear whether the lethality is due to an effect on Ant2 or sesB (or both).

(Peter et al., 2002, Schäfer et al., 1999.8.12)

FlyBase curator comment: the P{lacW} insertion results in homozygous semi-lethality, but since the insertion is within both the Ant2 and sesB transcription units, it is unclear whether the lethality is due to an effect on Ant2 or sesB (or both).

(Schäfer et al., 1999.6.15)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

11830

w^67c23 P{lacW}Ant2^G0126 sesB^G0126/FM7c

Notes on Origin

Discoverer

Comments

P{lacW} not verified as causing the lethality.

(Schäfer et al., 1999.6.15, Schäfer et al., 1999.8.12)

External Crossreferences and Linkouts ( 1 )

Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AJ426849

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Ant2^G0126

(Kanellopoulos et al., 2020)

l(1)G0126

(Peter et al., 2002)

l(1)G0126^G0126

Name Synonyms

Secondary FlyBase IDs

FBal0098193

References (6)

Report Sections

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