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General Information
Symbol
Dmel\shgAAA-JXT.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0154610
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt sequences drive expression of a mutated shg that contains mutations in evolutionarily conserved residues in the juxtamembrane domain (residues 1607-1609 are changed from ERD to AAA).

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

When shgAAA-JXT.Scer\UAS is driven by Scer\GAL4btl.PS tracheal fusion at the adherens junction in the dorsal trunk is disrupted. F-actin appears disorganised in the fusion cells, or forms weaker tracks than seen in wild-type. The fusion cells dp contact each other as seen in wild-type. Successful fusion events do occur, taking 2-3 hours to complete track initiation instead of about 1 hour in wild-type. Microtubule tracks are absent in 73% of fusion cell pairs, and in the remainder, microtubules are often abnormally assembled.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to rescue
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
shgAAA-JXT.Scer\UAS
shgAAA-JXT.UAS
Name Synonyms
Secondary FlyBase IDs
    References (1)