Allele Dmel\nvy^PDFKG38

General Information
Symbol	Dmel\nvy^PDFKG38	Species	D. melanogaster
Name		FlyBase ID	FBal0154822
Feature type	allele	Associated gene	Dmel\nvy

Allele class	loss of function allele
Mutagen
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class	loss of function allele (Terman and Kolodkin, 2004)
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	neuroanatomy defective (Terman and Kolodkin, 2004)
Phenotype Manifest In
	abdominal intersegmental nerve (Terman and Kolodkin, 2004) abdominal segmental nerve (Terman and Kolodkin, 2004) lateral longitudinal fascicle (Terman and Kolodkin, 2004) presumptive embryonic/larval central nervous system (Terman and Kolodkin, 2004) ventral nerve cord (Terman and Kolodkin, 2004)
Detailed Description
	Statement Reference Motor axons within the ISNb pathway often exit the ISN and ISNb in abnormal locations. They are excessively defasciculated and project incorrectly within the ventral musculature. Motor axons within SNa are also defasciculated, with inappropriate projections. Axons within the CNS also show abnormal projections and defasciculations, most notable in the lateral-most of the three longitudinal tracts detected with Fas2 1D4 antibody. The majority of defects are manifest as an increase in repulsion. (Terman and Kolodkin, 2004)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement Reference nvy^PDFKG38/nvy[+] is an enhancer of neuroanatomy defective phenotype of Scer\GAL4^how-24B/Scer\GAL4^how-24B, Sema-1a^Scer\UAS.cYa (Terman and Kolodkin, 2004)
Phenotype Manifest In
Enhancer of
Statement Reference nvy^PDFKG38/nvy[+] is an enhancer of abdominal intersegmental nerve phenotype of Scer\GAL4^how-24B/Scer\GAL4^how-24B, Sema-1a^Scer\UAS.cYa (Terman and Kolodkin, 2004) nvy^PDFKG38/nvy[+] is an enhancer of abdominal segmental nerve phenotype of Scer\GAL4^how-24B/Scer\GAL4^how-24B, Sema-1a^Scer\UAS.cYa (Terman and Kolodkin, 2004)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	nvy^PDFKG38
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Terman and Kolodkin, 2004, Science 303(5661): 1204--1207 Nervy links protein kinase A to plexin-mediated semaphorin repulsion. [FBrf0175134]

Allele Dmel\nvyPDFKG38

Allele Dmel\nvy^PDFKG38