Allele Dmel\dl^UY2278

General Information
Symbol	Dmel\dl^UY2278	Species	D. melanogaster
Name		FlyBase ID	FBal0155396
Feature type	allele	Associated gene	Dmel\dl

Allele class
Mutagen	P-element activity
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	P-element activity (Nicolai et al., 2003)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Insertion site maps to -311bp of the known/supposed transcription start site. (Nicolai et al., 2003)
Caused by insertion	P{Mae-UAS.6.11}dl^UY2278 (Nicolai et al., 2003, Ayyar et al., 2007)
Cytology
Phenotypic Data
Phenotypic Class
	neuroanatomy defective, with Scer\GAL4^7B (Nicolai et al., 2003) neuroanatomy defective, with Scer\GAL4^ey-OK107 (Nicolai et al., 2003) visible \| temperature conditional, with Scer\GAL4^sca-537.4 (Ayyar et al., 2007)
Phenotype Manifest In
	Kenyon cell, with Scer\GAL4^7B (Nicolai et al., 2003) Kenyon cell, with Scer\GAL4^ey-OK107 (Nicolai et al., 2003) macrochaeta \| ectopic \| temperature conditional, with Scer\GAL4^sca-537.4 (Ayyar et al., 2007) macrochaeta \| temperature conditional, with Scer\GAL4^sca-537.4 (Ayyar et al., 2007) mesothoracic tergum \| temperature conditional, with Scer\GAL4^sca-537.4 (Ayyar et al., 2007) mushroom body, with Scer\GAL4^7B (Nicolai et al., 2003) mushroom body, with Scer\GAL4^ey-OK107 (Nicolai et al., 2003) mushroom body & axon, with Scer\GAL4^7B (Nicolai et al., 2003) mushroom body & axon, with Scer\GAL4^ey-OK107 (Nicolai et al., 2003)
Detailed Description
	Statement Reference Expression of dl[UY2278] under the control of Scer\GAL4[sca-537.4] at 25[o]C results in loss of bristles over much of the notum, although the loss is greater in the lateral notum. Expression of dl[UY2278] under the control of Scer\GAL4[sca-537.4] at 18[o]C results in the generation of ectopic bristles on the medial notum in the dorsocentral and scutellar regions. (Ayyar et al., 2007) When expression is driven by Scer\GAL4^7B or Scer\GAL4^OK107, dl^UY2278 shows a mushroom body Class II phenotype; neuron number defects plus axonal growth and guidance defects. Axons seem defasciculated. (Nicolai et al., 2003)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 1 )
Bloomington	7350 y¹ w^67c23; P{Mae-UAS.6.11}dl^UY2278
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	dl^UY2278
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Ayyar et al., 2007, PLoS ONE 2(11): e1178 NF-kappaB/Rel-mediated regulation of the neural fate in Drosophila. [FBrf0210269] Nicolai et al., 2003, J. Neurobiol. 57(3): 291--302 Gain-of-function screen identifies a role of the Src64 oncogene in Drosophila mushroom body development. [FBrf0167790]

Allele Dmel\dlUY2278

Allele Dmel\dl^UY2278