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General Information
Symbol
Dmel\armi1
Species
D. melanogaster
Name
FlyBase ID
FBal0155637
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference

    Insertion in the 5' UTR of armi.

    Insertion components
    P{lacW}armi1
    Product class / Tool use(s)
    Encoded product / tool
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Eggs laid by armi1/armi72.1 females have dorsal appendage defects; 11.7% have fused dorsal appendages, 88.1% lack dorsal appendages and 0.2% have wild-type dorsal appendages.

    Only 2% of eggs derived from armi1/armi72.1 females have two wild-type dorsal appendages, compared with 11% if the females are fed caffeine.

    armi72.1/armi1 eggs show fused appendages in 67.6% of cases, no appendages in 28.9% of cases and the wild-type number of appendages in 3.5% of cases.

    In armi72.1/armi1 oocytes, both the anterior and later posterior microtubule-organizing centers are much less prominent than in wild-type oocytes.

    Homozygous females produce eggs where 67% completely lack dorsal appendages (indicating strong dorsal/ventral patterning defects).

    75% of progeny derived from homozygous males mated to wild-type females hatch. 67% of eggs derived from armi1 females lack dorsal appendages, while some of the eggs have wild-type or partially fused dorsal appendages.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    NOT suppressed by
    Statement
    Reference
    Phenotype Manifest In
    Suppressed by
    Statement
    Reference

    armi72.1/armi1 has microtubule organizing center & oocyte phenotype, suppressible by lokp6/lokp6/lokp6/lokp6

    armi72.1/armi1 has microtubule organizing center & oocyte phenotype, suppressible by mei-41D3/mei-41D3

    NOT suppressed by
    Statement
    Reference
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    The dorsal appendage defects seen in eggs laid by armi1/armi72.1 females are partly suppressed if the females are also homozygous for lokp6; 16.1% of the eggs have fused dorsal appendages, 7.3% lack dorsal appendages and 76.6% have wild-type dorsal appendages.

    56% of eggs derived from mei-41D3/mei-41D3 ; armi1/armi72.1 double mutant females have normal dorsal appendages, but the fraction of embryos with normal dorsal appendages increases to 83% if the females are fed caffeine.

    The fused dorsal appendage phenotype of armi72.1/armi1 eggs is suppressed in lokp6; armi72.1/armi1 eggs with 92% of double mutants showing wild-type appendage morphology.

    The mei-41D3 mutation partially suppresses the fused dorsal appendage phenotype of armi72.1/armi1 eggs; 56% of mei-41D3; armi72.1/armi1 eggs show wild-type appendage morphology.

    The fused dorsal appendage phenotype of armi72.1/armi1 eggs is not suppressed in mei-W681/mei-W68k05603; armi72.1/armi1 eggs.

    The microtubule-organizing center phenotype of armi72.1/armi1 oocytes is suppressed by the lokp6 mutation.

    The microtubule-organizing center phenotype of armi72.1/armi1 oocytes is partially suppressed by the mei-41D3 mutation.

    armi1 osk1 double mutant ovaries have microtubule defects that are cytologically identical to the armi single mutant phenotype.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Partially rescued by
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer
    Comments
    Comments

    Excision of the insertion can revert the mutant phenotype.

    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    References (16)