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General Information
Symbol
Dmel\Rho1Ebr246
Species
D. melanogaster
Name
FlyBase ID
FBal0155976
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

3% of heterozygotes show a malformed leg phenotype. Homozygotes show 100% embryonic lethality. Homozygous embryos show an anterior open cuticle phenotype and germband retraction is incomplete.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

Rho1[+]/Rho1Ebr246 is an enhancer of visible phenotype of br1

Other
Statement
Reference
Phenotype Manifest In
Enhancer of
Statement
Reference

Rho1[+]/Rho1Ebr246 is an enhancer of leg phenotype of br1

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

18% of br1 ; Rho1Ebr246/+ flies show a malformed leg phenotype. The predominant leg phenotype in br1/Y ; Rho1Ebr246/+ flies is short, fat femurs and tibias. 9% of br5/+ ; Rho1Ebr246/+ flies show a malformed leg phenotype. 17% of Rho1Ebr246 RhoGEF204291 double heterozygotes show a malformed leg phenotype in at least one leg. 63% of Rho1Ebr246 RhoGEF211-3 double heterozygotes show a malformed leg phenotype in at least one leg. 83% of Rho1Ebr246 zipEbr double heterozygotes show a malformed leg phenotype in at least one leg. 6% of Rho1Ebr246 zip1 double heterozygotes show a malformed leg phenotype in at least one leg. 90% of Rho1Ebr246 zip33-1 double heterozygotes show a malformed leg phenotype in at least one leg.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Selected as: a mutation that enhances the br1 malformed leg phenotype.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Rho1E(br)246
Rho1Ebr246
Name Synonyms
Secondary FlyBase IDs
    References (1)