Allele Dmel\Pu^EY02616a

General Information
Symbol	Dmel\Pu^EY02616a	Species	D. melanogaster
Name		FlyBase ID	FBal0156013
Feature type	allele	Associated gene	Dmel\Pu

Map ( GBrowse )	Untitled Document
Allele class
Mutagen	P-element activity
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	P-element activity (Gene Disruption Project members, 2001-)
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site 2R:17,065,305..17,065,305 (Gene Disruption Project members, 2001-, Ferdousy et al., 2011)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	P{EPgy2}Pu^EY02616a (Gene Disruption Project members, 2001-, Ferdousy et al., 2011)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference Pu[EY02616a] heterozygotes do not exhibit a eye degeneration phenotype. (Ferdousy et al., 2011)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Statement Reference Pu^EY02616a is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, Ube3a^{Scer\UAS.T:Zzzz\FLAG} (Ferdousy et al., 2011) Pu^EY02616a is an enhancer of interommatidial bristle phenotype of Scer\GAL4^GMR.PF, Ube3a^{Scer\UAS.T:Zzzz\FLAG} (Ferdousy et al., 2011)
Additional Comments
Genetic Interactions
Statement Reference A Pu[EY02616a] heterozygous background enhances the Scer\GAL4[GMR.PF]-> Ube3a[CA.Scer\UAS.T:Zzzz\FLAG] rough eye phenotype, causing a glazed appearance, loss of inter-ommatidial bristles and a yellowish discoloration, indicative of underlying neurodegeneration. (Ferdousy et al., 2011)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 1 )
Bloomington	15576 y¹ w^67c23; P{EPgy2}Pu^EY02616a
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Pu^EY02616a
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Ferdousy et al., 2011, Neurobiol. Disease 41(3): 669--677 Drosophila Ube3a regulates monoamine synthesis by increasing GTP cyclohydrolase I activity via a non-ubiquitin ligase mechanism. [FBrf0212886]
Personal communication to FlyBase	Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177]

Allele Dmel\PuEY02616a

Allele Dmel\Pu^EY02616a