A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Allele Dmel\Psn143

General Information
SymbolDmel\Psn143SpeciesD. melanogaster
NameFlyBase IDFBal0156040
Feature typealleleAssociated geneDmel\Psn
Allele classloss of function allele
Mutagen
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Description
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FB2013_03
FB2013_02
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hide Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Progenitor genotype
Nature of the lesion
Statement
Reference
Deletion and/or splice site mutation resulting in deletion of the amino acids between the first transmembrane domain and the middle of the fourth transmembrane domain.
Cytology
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Statement
Reference
Psn[9]/Psn[143] trans-heterozygotes display normal thorax morphology.
Heterozygotes show no visible phenotypes. Psn9/Psn143 flies have a reduced and roughened eye and distal wing vein thickening, while the notum is relatively normal.
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hideEnhanced by
Statement
Reference
Psn9/Psn143 has visible phenotype, enhanceable by AP-1μSAE-10
Psn9/Psn143 has visible phenotype, enhanceable by AP-1μSHE-11
Psn9/Psn143 has visible phenotype, enhanceable by dacMEE-2
Psn9/Psn143 has visible phenotype, enhanceable by dacMHE-1
Psn9/Psn143 has visible phenotype, enhanceable by dacSFE-8
Psn9/Psn143 has visible phenotype, enhanceable by DlMIE-22
Psn9/Psn143 has visible phenotype, enhanceable by DlPFE-6
Psn9/Psn143 has visible phenotype, enhanceable by DlPGE-2
Psn9/Psn143 has visible phenotype, enhanceable by DlSDE-4
Psn9/Psn143 has visible phenotype, enhanceable by DlSHE-11
Psn9/Psn143 has visible phenotype, enhanceable by dpPGE-8
Psn9/Psn143 has visible phenotype, enhanceable by eyaSJE-1
Psn9/Psn143 has visible phenotype, enhanceable by eyaSLE-2
Psn9/Psn143 has visible phenotype, enhanceable by glSAE-9
Psn9/Psn143 has visible phenotype, enhanceable by hhPIE-7
Psn9/Psn143 has visible phenotype, enhanceable by hhSCE-2
Psn9/Psn143 has visible phenotype, enhanceable by hhSFE-4
Psn9/Psn143 has visible phenotype, enhanceable by hhSGE-2
Psn9/Psn143 has visible phenotype, enhanceable by hhSHE-2
Psn9/Psn143 has visible phenotype, enhanceable by hhSLE-1
Psn9/Psn143 has visible phenotype, enhanceable by kkvSIE-29
Psn9/Psn143 has visible phenotype, enhanceable by nctPIE-6
Psn9/Psn143 has visible phenotype, enhanceable by nctSGE-3
Psn9/Psn143 has visible phenotype, enhanceable by nctSGE-8
Psn9/Psn143 has visible phenotype, enhanceable by nctSGE-9
Psn9/Psn143 has visible phenotype, enhanceable by nctSGE-10
Psn9/Psn143 has visible phenotype, enhanceable by nctSIE-22
Psn9/Psn143 has visible phenotype, enhanceable by nctSIE-28
Psn9/Psn143 has visible phenotype, enhanceable by opaSIE-19
Psn9/Psn143 has visible phenotype, enhanceable by opaSIE-24
Psn9/Psn143 has visible phenotype, enhanceable by opaSJE-2
Psn9/Psn143 has visible phenotype, enhanceable by opaSKE-5
Psn9/Psn143 has visible phenotype, enhanceable by RPIE-6
Psn9/Psn143 has visible phenotype, enhanceable by Ras85DMAE-2
Psn9/Psn143 has visible phenotype, enhanceable by Ras85DMDE-7
Psn9/Psn143 has visible phenotype, enhanceable by Sunspecified
Psn9/Psn143 has visible phenotype, enhanceable by soSHE-7
Psn9/Psn143 has visible phenotype, enhanceable by soSKE-1
Psn9/Psn143 has visible phenotype, enhanceable by Spt5MGE-3
Psn9/Psn143 has visible phenotype, enhanceable by Spt5SIE-27
Psn9/Psn143 has visible phenotype, enhanceable by vgSDE-1
Psn9/Psn143 has visible phenotype, enhanceable by vgSGE-11
Psn9/Psn143 has visible phenotype, enhanceable by γTub23Cbmps3
Psn9/Psn143 has visible phenotype, enhanceable by γTub23Cbmps4
Psn9/Psn143 has visible phenotype, enhanceable by γTub23Cbmps5
hideSuppressed by
Statement
Reference
Psn9/Psn143 has visible phenotype, suppressible by HSDS-1
Psn9/Psn143 has visible phenotype, suppressible by HSLS-1
hideEnhancer of
Statement
Reference
hideOther
Statement
Reference
Psn143/Psn[+], opaA3 has visible phenotype
Psn143/Psn[+], opaB28 has visible phenotype
hide Phenotype Manifest In
hideEnhanced by
Statement
Reference
Psn9/Psn143 has eye phenotype, enhanceable by AP-1μSAE-10
Psn9/Psn143 has eye phenotype, enhanceable by AP-1μSHE-11
Psn9/Psn143 has eye phenotype, enhanceable by dacMEE-2
Psn9/Psn143 has eye phenotype, enhanceable by dacMHE-1
Psn9/Psn143 has eye phenotype, enhanceable by dacSFE-8
Psn9/Psn143 has eye phenotype, enhanceable by DlMIE-22
Psn9/Psn143 has eye phenotype, enhanceable by DlPFE-6
Psn9/Psn143 has eye phenotype, enhanceable by DlPGE-2
Psn9/Psn143 has eye phenotype, enhanceable by DlSDE-4
Psn9/Psn143 has eye phenotype, enhanceable by DlSHE-11
Psn9/Psn143 has eye phenotype, enhanceable by dpPGE-8
Psn9/Psn143 has eye phenotype, enhanceable by eyaSJE-1
Psn9/Psn143 has eye phenotype, enhanceable by eyaSLE-2
Psn9/Psn143 has eye phenotype, enhanceable by glSAE-9
Psn9/Psn143 has eye phenotype, enhanceable by hhPIE-7
Psn9/Psn143 has eye phenotype, enhanceable by hhSCE-2
Psn9/Psn143 has eye phenotype, enhanceable by hhSFE-4
Psn9/Psn143 has eye phenotype, enhanceable by hhSGE-2
Psn9/Psn143 has eye phenotype, enhanceable by hhSHE-2
Psn9/Psn143 has eye phenotype, enhanceable by hhSLE-1
Psn9/Psn143 has eye phenotype, enhanceable by kkvSIE-29
Psn9/Psn143 has eye phenotype, enhanceable by nctPIE-6
Psn9/Psn143 has eye phenotype, enhanceable by nctSGE-3
Psn9/Psn143 has eye phenotype, enhanceable by nctSGE-8
Psn9/Psn143 has eye phenotype, enhanceable by nctSGE-9
Psn9/Psn143 has eye phenotype, enhanceable by nctSGE-10
Psn9/Psn143 has eye phenotype, enhanceable by nctSIE-22
Psn9/Psn143 has eye phenotype, enhanceable by nctSIE-28
Psn9/Psn143 has eye phenotype, enhanceable by opaSIE-19
Psn9/Psn143 has eye phenotype, enhanceable by opaSIE-24
Psn9/Psn143 has eye phenotype, enhanceable by opaSJE-2
Psn9/Psn143 has eye phenotype, enhanceable by opaSKE-5
Psn9/Psn143 has eye phenotype, enhanceable by RPIE-6
Psn9/Psn143 has eye phenotype, enhanceable by Ras85DMAE-2
Psn9/Psn143 has eye phenotype, enhanceable by Ras85DMDE-7
Psn9/Psn143 has eye phenotype, enhanceable by Sunspecified
Psn9/Psn143 has eye phenotype, enhanceable by soSHE-7
Psn9/Psn143 has eye phenotype, enhanceable by soSKE-1
Psn9/Psn143 has eye phenotype, enhanceable by Spt5MGE-3
Psn9/Psn143 has eye phenotype, enhanceable by Spt5SIE-27
Psn9/Psn143 has eye phenotype, enhanceable by vgSDE-1
Psn9/Psn143 has eye phenotype, enhanceable by vgSGE-11
Psn9/Psn143 has eye phenotype, enhanceable by γTub23Cbmps3
Psn9/Psn143 has eye phenotype, enhanceable by γTub23Cbmps4
Psn9/Psn143 has eye phenotype, enhanceable by γTub23Cbmps5
hideNOT Enhanced by
Statement
Reference
Psn9/Psn143 has phenotype, non-enhanceable by aph-1[+]/aph-1D35
hideSuppressed by
Statement
Reference
Psn9/Psn143 has eye phenotype, suppressible by HSDS-1
Psn9/Psn143 has eye phenotype, suppressible by HSLS-1
hideNOT suppressed by
Statement
Reference
Psn9/Psn143 has phenotype, non-suppressible by aph-1[+]/aph-1D35
hideEnhancer of
Statement
Reference
Psn143/Psn[+] is an enhancer of eye phenotype of Scer\GAL4hs.2sev, hbsScer\UAS.cDa
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Statement
Reference
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Statement
Reference
Psn[143]/+ dominantly enhances the frequency of R3-R3 symmetrical clusters induced by Scer\GAL4[hs.2sev]>hbs[VDRC.cUa]. Psn[143]/+ enhances the Scer\GAL4[hs.2sev]>hbs[Scer\UAS.cDa]-induced planar cell polarity (PCP) phenotype in the eye. Psn[9]/Psn[143] strongly enhances the thoracic bristle loss of Df(2R)hbs[j5]/Df(2R)ED2423 mutants. Psn[9]/Psn[143] strongly enhances the thoracic bristle loss of hbs[459]/Df(2R)ED2423 mutants.
γTub23Cbmps1 ; Psn143/+ flies have bumps and notching on the wing. γTub23Cbmps2 ; Psn143/+ flies have bumps and notching on the wing. opaA3 Psn143/+ flies have tufted vibrissae. opaB28 Psn143/+ flies have tufted vibrissae. dpMFE-1 ; Psn9/Psn143 flies have pits in the notum. dpPIE-10 ; Psn9/Psn143 flies have pits in the notum. γTub23Cbmps3 ; Psn9/Psn143 flies have bumps and notching on the wing and wing vein thickening. γTub23Cbmps4 ; Psn9/Psn143 flies have bumps and notching on the wing and wing vein thickening. vgPHE-4 ; Psn9/Psn143 flies have notches on the wing. vgSDE-1 ; Psn9/Psn143 flies have notches on the wing. vgSGE-4 ; Psn9/Psn143 flies have notches on the wing. vgSGE-11 ; Psn9/Psn143 flies have notches on the wing. AP-47SAE-10 Psn9/Psn143 flies show wing vein thickening. AP-47SHE-11 Psn9/Psn143 flies show wing vein thickening and low penetrance pupal lethality. DlMIE-22 Psn9/Psn143 flies show wing vein thickening. DlPFE-6 Psn9/Psn143 flies show wing vein thickening. DlPGE-2 Psn9/Psn143 flies show wing vein thickening. DlSDE-4 Psn9/Psn143 flies show wing vein thickening. DlSHE-5 Psn9/Psn143 flies have held out wings which show notching. DlSHE-11 Psn9/Psn143 flies show wing vein thickening and low penetrance pupal lethality. DlSIE-36 Psn9/Psn143 flies show wing vein thickening and low penetrance pupal lethality. HPFE-1 Psn9/Psn143 flies show bristle shaft to socket transformations and wing vein loss. HPGE-1 Psn9/Psn143 flies show bristle shaft to socket transformations and wing vein loss. HPGE-4 Psn9/Psn143 flies show bristle shaft to socket transformations and wing vein loss. HPGE-6 Psn9/Psn143 flies show bristle shaft to socket transformations and wing vein loss. HSDS-1 Psn9/Psn143 flies show bristle shaft to socket transformations and wing vein loss. HSLS-1 Psn9/Psn143 flies show bristle shaft to socket transformations and wing vein loss. hhPIE-7 Psn9/Psn143 flies have extra vein material between wing veins 2 and 3. hhSCE-2 Psn9/Psn143 flies show wing notching. nctSGE-8 Psn9/Psn143 flies show wing vein thickening and notching of the wing. nctSGE-9 Psn9/Psn143 flies show wing vein thickening and notching of the wing. nctSIE-28 Psn9/Psn143 flies show wing vein thickening and notching of the wing. nctSIE-22 Psn9/Psn143 flies show notching of the wing and some microchaetae are missing. opaSIE-19 Psn9/Psn143 flies have tufted vibrissae. opaSIE-24 Psn9/Psn143 flies have tufted vibrissae. opaSJE-2 Psn9/Psn143 flies have tufted vibrissae and wing notching. opaSKE-5 Psn9/Psn143 flies have tufted vibrissae. vgPHE-4 ; Psn143/+ flies show mild wing nicking. AP-47SAE-10/AP-47SHE-11 Psn9/Psn143 flies have dorsal and ventral wing notching, enhanced wing vein thickening and show loss of notal microchaetae.
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Bloomington
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Reported As
Symbol Synonym
Name Synonym
Secondary FlyBase IDs
hide References ( 3 )
Research paper
Singh and Mlodzik, 2012, Dev. Cell 23(1): 82--96
Hibris, a Drosophila Nephrin Homolog, Is Required for Presenilin-Mediated Notch and APP-like Cleavages. [FBrf0218978]
Mahoney et al., 2006, Genetics 172(4): 2309--2324
Presenilin-based genetic screens in Drosophila melanogaster identify novel Notch pathway modifiers. [FBrf0190744]
Personal communication to FlyBase
Parks, 2004.5.6, Psn<up>9</up>, Psn<up>143</up>, Psn<up>145</up> and Psn<up>227</up>.
Psn9, Psn143, Psn145 and Psn227. [FBrf0178835]