Allele Dmel\Med^G112

General Information
Symbol	Dmel\Med^G112	Species	D. melanogaster
Name		FlyBase ID	FBal0156262
Feature type	allele	Associated gene	Dmel\Med

Map ( GBrowse )
Allele class
Mutagen
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References point mutation 3R:27,439,597..27,439,598 evidence=experimental comment=Position of mutation on reference sequence inferred by FlyBase curator based on author statement. Mutation in the splice donor site of exon 4. Exon 4 of Med-PB used because authors appear to be referring to this transcript (see Med^C246) (McCabe et al., 2004)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Mutation in the splice donor site of exon 4. (McCabe et al., 2004)
Cytology
Phenotypic Data
Phenotypic Class
	neuroanatomy defective (McCabe et al., 2004)
Phenotype Manifest In
	bouton (McCabe et al., 2004) neuromuscular junction (McCabe et al., 2004)
Detailed Description
	Statement Reference Mutants show a dramatic reduction in the number of neuromuscular junction synaptic boutons. (McCabe et al., 2004)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Med^G112 (Ball et al., 2010)
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Ball et al., 2010, Neuron 66(4): 536--549 Retrograde BMP Signaling Controls Synaptic Growth at the NMJ by Regulating Trio Expression in Motor Neurons. [FBrf0210920] McCabe et al., 2004, Neuron 41(6): 891--905 Highwire regulates presynaptic BMP signaling essential for synaptic growth. [FBrf0175022]

Allele Dmel\MedG112

Allele Dmel\Med^G112