FB2025_01 , released February 20, 2025
Allele: Dmel\Micalunspecified
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General Information
Symbol
Dmel\Micalunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0156280
Feature type
allele
Associated gene
Dmel\Mical
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        F-actin bundles in the developing bristles of mutant adults are significantly larger than normal, and are intersecting.

        (Hung et al., 2010)

        Mutant larvae have well-coordinated and regular peristaltic movements when crawling on fruit agar plates, but the vigour of the peristalsis is strongly reduced compared to wild type. Contraction waves advance more slowly compared to actively migrating wild-type larvae.

        (Beuchle et al., 2007)

        Embryos mutant for loss or gain of function mutations show axon guidance defects in ISNb, SNa and the CNS. For loss of function mutants the majority of defects are manifest as a decrease in repulsion. For gain of function mutants the majority of defects are manifest as an increase in repulsion.

        (Terman and Kolodkin, 2004)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        Statement
        Reference

        Micalunspecified/Micalunspecified is a suppressor of visible phenotype of PlexAUAS.Tag:HA, Scer\GAL4B11-98

        (Hung et al., 2010)
        Phenotype Manifest In
        Suppressor of
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The branched bristle phenotype caused by expression of two copies of plexAScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4B11-98 is suppressed if the flies are also homozygous for Micalunspecified.

        (Hung et al., 2010)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        MICALunspecified
        Micalunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (3)