Allele Hsap\ATXN8OS^{CTG112.Scer\UAS}

General Information
Symbol	Hsap\ATXN8OS^{CTG112.Scer\UAS}	Species	H. sapiens
Name		FlyBase ID	FBal0156378
Feature type	allele	Associated gene	Hsap\ATXN8OS

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Mutsuddi et al., 2004)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: Scer\UAS regulatory sequences drive expression of exons D, C3, C2 and A of a Hsap\SCA8 cDNA. This construct contains a pathogenic, expanded configuration of CTG repeats which has the configuration CTA₃CTG₅CCG₃CTG₁₁₂. (Mutsuddi et al., 2004)
Carried in construct	P{UAS-SCA8.CTG112} (Mutsuddi et al., 2004)
Cytology
Phenotypic Data
Phenotypic Class
	neuroanatomy defective, with Scer\GAL4^GMR.PF (Mutsuddi et al., 2004) visible, with Scer\GAL4^GMR.PF (Mutsuddi et al., 2004)
Phenotype Manifest In
	eye photoreceptor cell & neuron, with Scer\GAL4^GMR.PF (Mutsuddi et al., 2004) interommatidial bristle, with Scer\GAL4^GMR.PF (Mutsuddi et al., 2004) ommatidium, with Scer\GAL4^GMR.PF (Mutsuddi et al., 2004) pigment cell, with Scer\GAL4^GMR.PF (Mutsuddi et al., 2004) retina, with Scer\GAL4^GMR.PF (Mutsuddi et al., 2004)
Detailed Description
	Statement Reference Expression of Hsap\SCA8^{CTG112.Scer\UAS} under the control of Scer\GAL4^GMR.PF results in disorganisation of the ommatidia and mechanosensory bristles of the eye, with the central portion of the eye being most severely affected. The penetrance of the phenotype is variable. The retina of 1- to 2-day old flies expressing Hsap\SCA8^{CTG112.Scer\UAS} under the control of Scer\GAL4^GMR.PF shows mild disorganisation with a loss of photoreceptor neurons and pigment cells. This retinal degeneration becomes progressively more severe as the flies age, with photoreceptor neurons becoming rod shaped and fragmented, resulting in vacuole formation. The recruitment and differentiation of photoreceptor neurons in larval eye discs expressing Hsap\SCA8^{CTG112.Scer\UAS} under the control of Scer\GAL4^GMR.PF appears to be normal, with degeneration of the photoreceptors appearing to begin during the pupal stages. (Mutsuddi et al., 2004)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement Reference Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by Aats-thr[+]/Aats-thr^k04203 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by Ate1[+]/Ate1^k10809 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by Eip75B[+]/Eip75B⁰⁷⁰⁴¹ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by hoip[+]/hoip^k07104 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by Inr-a^k08015/Pcf11[+] (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by l(2)k07433[+]/Patronin^k07433 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by l(2)k10217^k10217/l(2)k10217[+]/l(2)k10217^k10217 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by l(3)j1E7[+]/l(3)j1E7^j1E7 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by lolal^k02512/lolal[+] (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by mbl^E16 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by mbl^E27 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by mbl^k01212 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by mbl^k07103 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by px[+]/px^k08316 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by Sac1[+]/Sac1^BG02228 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by spen^AH393 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by spen^XFM911 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by spoon^KG02745 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by stau¹ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by stau² (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by stau^ry9 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by ttv^k11904/ttv[+] (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, enhanceable by Vha36-1^k07207/Vha36[+] (Mutsuddi et al., 2004)
NOT Enhanced by
Statement Reference Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by apt⁰³⁰⁴¹ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by apt^EP2339, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by apt^k15608 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by aret⁰¹²⁸⁴ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by aret^BG00614 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by B52^s2249 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by cpo⁰¹⁴³² (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by egl¹²⁸⁶ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by egl^EP938, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by eIF-4a^EP1011, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by eIF-4a^k01501 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by eIF-4E⁰⁷²³⁸ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by eIF-4E^EP568, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by elav⁴ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by elav^C155 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by Fmr1^Δ50M/Df(3R)by62 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by heph² (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by msi¹ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by msi² (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by mub⁰⁴⁰⁹³ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by nonA^4b18 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by orb^dec (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by P{EP}RnpS1^EP1082, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by pum³ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by pum⁰¹⁶⁸⁸ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by qkr58E-1^EP2103, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-enhanceable by Sxl^fs3 (Mutsuddi et al., 2004)
Suppressed by
Statement Reference Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, suppressible by atms[+]/atms^rK509 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, suppressible by Cas[+]/Cas^k03902 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, suppressible by hrg^k07619/hrg[+] (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, suppressible by Int6[+]/Int6¹⁰⁵⁴⁷ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, suppressible by l(2)k04308^k04308/l(2)k04308[+] (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, suppressible by l(2)k07824[+]/wcd^k07824 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, suppressible by l(2)k09854^k09854/l(2)k09854[+] (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, suppressible by l(3)09070⁰⁹⁰⁷⁰/l(3)09070[+] (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, suppressible by l(3)L1820[+]/l(3)L1820^L1820 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, suppressible by mod(mdg4)^L3101/mod(mdg4)[+] (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, suppressible by Psc[+]/Psc^k07834 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, suppressible by RnrL^k06709/RnrL[+] (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, suppressible by S6k[+]/S6k⁰⁷⁰⁸⁴ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, suppressible by spoon^EP1400, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Mutsuddi et al., 2004)
NOT suppressed by
Statement Reference Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by apt⁰³⁰⁴¹ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by apt^EP2339, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by apt^k15608 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by aret⁰¹²⁸⁴ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by aret^BG00614 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by B52^s2249 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by cpo⁰¹⁴³² (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by egl¹²⁸⁶ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by egl^EP938, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by eIF-4a^EP1011, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by eIF-4a^k01501 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by eIF-4E⁰⁷²³⁸ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by eIF-4E^EP568, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by elav⁴ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by elav^C155 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by Fmr1^Δ50M/Df(3R)by62 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by heph² (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by msi¹ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by msi² (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by mub⁰⁴⁰⁹³ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by nonA^4b18 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by orb^dec (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by P{EP}RnpS1^EP1082, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by pum³ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by pum⁰¹⁶⁸⁸ (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by qkr58E-1^EP2103, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has neuroanatomy defective phenotype, non-suppressible by Sxl^fs3 (Mutsuddi et al., 2004)
Phenotype Manifest In
Enhanced by
Statement Reference Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye photoreceptor cell phenotype, enhanceable by mbl^E16 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by spen^AH393 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by spoon^KG02745 (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by stau² (Mutsuddi et al., 2004) Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has pigment cell phenotype, enhanceable by mbl^E16 (Mutsuddi et al., 2004)
Suppressed by
Statement Reference Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, suppressible by spoon^EP1400, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Mutsuddi et al., 2004)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Hsap\ATXN8OS^{CTG112.Scer\UAS} Hsap\SCA8^{CTG112.Scer\UAS}
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Mutsuddi et al., 2004, Curr. Biol. 14(4): 302--308 The spinocerebellar ataxia 8 noncoding RNA causes neurodegeneration and associates with staufen in Drosophila. [FBrf0174476]

Allele Hsap\ATXN8OSCTG112.Scer\UAS

Allele Hsap\ATXN8OS^{CTG112.Scer\UAS}