Allele Dmel\GNBP1^Scer\UAS.cGa

General Information
Symbol	Dmel\GNBP1^Scer\UAS.cGa	Species	D. melanogaster
Name		FlyBase ID	FBal0156445
Feature type	allele	Associated gene	Dmel\GNBP1

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Gobert et al., 2003)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: Expression of GNBP1 coding region is governed by Scer\UAS regulatory sequences. (Gobert et al., 2003)
Carried in construct	P{UAS-GNBP1.G} (Jang et al., 2006, Buchon et al., 2009, Gobert et al., 2003, Kambris et al., 2006, Kambris et al., 2006, El Chamy et al., 2008, Wang et al., 2008)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	Scer\GAL4^hs.PB/GNBP1^Scer\UAS.cGa rescues GNBP1^e03371 (Gobert et al., 2003)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	GNBP1^Scer\UAS.cGa GNBP1^UAS (Fullaondo et al., 2011)
Name Synonym
Secondary FlyBase IDs

References ( 8 )
Research paper	Fullaondo et al., 2011, Mol. Cell. Biol. 31(14): 2960--2972 Spn1 Regulates the GNBP3-Dependent Toll Signaling Pathway in Drosophila melanogaster. [FBrf0214037] Buchon et al., 2009, Proc. Natl. Acad. Sci. U.S.A. 106(30): 12442--12447 A single modular serine protease integrates signals from pattern-recognition receptors upstream of the Drosophila Toll pathway. [FBrf0208605] El Chamy et al., 2008, Nat. Immunol. 9(10): 1165--1170 Sensing of 'danger signals' and pathogen-associated molecular patterns defines binary signaling pathways 'upstream' of Toll. [FBrf0207060] Wang et al., 2008, Proc. Natl. Acad. Sci. U.S.A. 105(33): 11881--11886 Peptidoglycan recognition protein-SD provides versatility of receptor formation in Drosophila immunity. [FBrf0205873] Jang et al., 2006, Dev. Cell 10(1): 45--55 A Spatzle-processing enzyme required for toll signaling activation in Drosophila innate immunity. [FBrf0190205] Kambris et al., 2006, Curr. Biol. 16(8): 808--813 Drosophila immunity: a large-scale in vivo RNAi screen identifies five serine proteases required for Toll activation. [FBrf0190023] Gobert et al., 2003, Science 302(5653): 2126--2130 Dual activation of the Drosophila toll pathway by two pattern recognition receptors. [FBrf0168033]
Supplementary material	Kambris et al., 2006, Curr. Biol. 16(8): Document S1. Two Figures and Supplemental Experimental Procedures. [FBrf0199186]

Allele Dmel\GNBP1Scer\UAS.cGa

Allele Dmel\GNBP1^Scer\UAS.cGa