FB2025_01 , released February 20, 2025
Allele: Dmel\EloBEP3132
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General Information
Symbol
Dmel\EloBEP3132
Species
D. melanogaster
Name
FlyBase ID
FBal0156465
Feature type
allele
Associated gene
Dmel\EloB
Associated Insertion(s)
P{EP}EloBEP3132
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(Rougeot et al., 2013)
Mutagen
P-element activity
(FlyBase, 1996-)
Progenitor genotype
Associated Insertion(s)
P{EP}EloBEP3132
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous animals die before the third larval instar.

      28.8% of heterozygous females have a truncated L5 wing vein.

      The single EloBEP3132/Df(3R)BSC518 escaper recovered had a truncated L5 wing vein.

      (Rougeot et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Elongin-B[+]/EloBEP3132 is a suppressor | partially of visible | dominant phenotype of corto07128b

      (Rougeot et al., 2013)

      Elongin-B[+]/EloBEP3132 is a suppressor of visible | dominant phenotype of cortol1

      (Rougeot et al., 2013)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Elongin-B[+]/EloBEP3132 is a suppressor | partially of wing vein | ectopic phenotype of corto07128b

      (Rougeot et al., 2013)

      Elongin-B[+]/EloBEP3132 is a suppressor of wing vein | ectopic phenotype of cortol1

      (Rougeot et al., 2013)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The penetrance of the ectopic wing vein phenotype seen in corto07128b/+ females (over 90% penetrance) is reduced if they are also heterozygous for EloBEP3132 (26.6% penetrance).

      The ectopic wing vein phenotype seen in cortol1/+ females is suppressed if they are also heterozygous for EloBEP3132.

      (Rougeot et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Elo-BEP3132
      (Dobi et al., 2014)
      EloBEP3132
      (Rougeot et al., 2013)
      Elongin-BEP3132
      Name Synonyms
      Secondary FlyBase IDs
        References (3)