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General Information
Symbol
Dmel\E(br)420Ebr420
Species
D. melanogaster
Name
FlyBase ID
FBal0156618
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

2% of heterozygotes show a malformed leg phenotype. Homozygotes show 3 +/- 1% embryonic lethality and 99+/- 1% of homozygous larvae fail to form pupae. Homozygous embryos have no discernible mutant phenotype.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

E(br)420[+]/E(br)420Ebr420 is an enhancer of visible phenotype of br1

Other
Statement
Reference
Phenotype Manifest In
Enhancer of
Statement
Reference

E(br)420[+]/E(br)420Ebr420 is an enhancer of leg phenotype of br1

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

24% of br1 ; E(br)420Ebr420/+ flies show a malformed leg phenotype. The predominant leg phenotype in br1/Y ; E(br)420Ebr420/+ flies is short thin tibias and tarsal segments (and sometimes these elements are missing), predominantly in the first leg. 4% of br5/+ ; E(br)420Ebr420/+ flies show a malformed leg phenotype. 21% of E(br)420Ebr420 Rho1J3.8 double heterozygotes show a malformed leg phenotype in at least one leg. 2% of E(br)420Ebr420 Rho1k02107b double heterozygotes show a malformed leg phenotype in at least one leg. 1% of E(br)420Ebr420 Rho1E3.10 double heterozygotes show a malformed leg phenotype in at least one leg. 3% of E(br)420Ebr420 RhoGEF204291 double heterozygotes show a malformed leg phenotype in at least one leg. 6% of E(br)420Ebr420 RhoGEF211-3 double heterozygotes show a malformed leg phenotype in at least one leg. 15% of E(br)420Ebr420 zipEbr double heterozygotes show a malformed leg phenotype in at least one leg. 2% of E(br)420Ebr420 zip1 double heterozygotes show a malformed leg phenotype in at least one leg. 3% of E(br)420Ebr420 zip33-1 double heterozygotes show a malformed leg phenotype in at least one leg.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Selected as: a mutation that enhances the br1 malformed leg phenotype.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
E(br)420Ebr420
Name Synonyms
Secondary FlyBase IDs
    References (1)