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General Information
Symbol
Dmel\wakeEY02219
Species
D. melanogaster
Name
FlyBase ID
FBal0157140
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
EY02219
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Insertion within the wake coding region.

Insertion components
P{EPgy2}wakeEY02219
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

wakeEY02219 homozygous adults exhibit a significant decrease in sleep duration during both day time and night time (ZT1-12 and ZT13-24, respectively) and a significant increase in sleep latency period (females only), as compared to controls.

wakeEY02219/wakeGS17103 and homozygous wakeEY02219 females show a significant reduction in total daily sleep relative to controls. Sleep bout duration is significantly decreased but there is no significant change in sleep bout number. Sleep latency is significantly increased.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference
Suppressor of
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

wakeEY02219, Fbxl4Δ45 double homozygotes do not exhibit the sleep defects exhibited by either of the single homozygotes.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
Comments
Comments

Precise excision of the P{EPgy2}wakeEY02219 insertion reverts the reduced sleep and increased sleep latency seen in mutant flies.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (7)
Reported As
Symbol Synonym
CG17623EY02219
CG42686EY02219
CG45058EY02219
wakeEY02219
wakeey02219
Name Synonyms
Secondary FlyBase IDs
    References (4)