FB2021_06, released December 14, 2021
Allele: Dmel\AP-1μSHE-11
Allele: Dmel\AP-1μSHE-11
37 nucleotide deletion resulting in the deletion of amino acids 146 to 158 and a frameshift.
Deletion of sequences encoding amino acid residues 146-158, resulting in a predicted frameshift.
37 nucleotide deletion resulting in the deletion of amino acids 146 to 158 and a frameshift.
viable (with AP-1μEP1112)
AP-1μSHE-11 ddaC neuron clones within mosaic individuals do not present significant dendrite pruning defects at 16h after puparium formation, as compared to controls.
Eyes containing AP-47SHE-11 clones are rough.
Irregularly aligned photoreceptor cells are observed in AP-47SHE-11 eye disc clones.
11% of AP-47SHE-11 mutant adult sensory organ clones contain extra socket cells.
Homozygous AP-47SHE-11 mutant clones cells induced in third instar larval salivary gland cells either lack detectable glue granules or accumulate small granules in the cytoplasm. AP-47SHE-11 mutant cells also appear smaller than wild type. AP-47SHE-11/+ cells are of an intermediate size, suggesting that AP-47SHE-11 is dosage dependent.
The glue granules of AP-47SHE-11/AP-47EP1112 mutant third instar larvae are smaller than wild type, but larger than those seen in homozygous AP-47SHE-11 mutant larvae.
Salivary gland cell growth (which normally occurs in the third larval instar, starting at the distal end of the gland) is defective in AP-47EP1112/AP-47SHE-11 third instar larvae.
AP-1μSHE-11 is an enhancer of visible phenotype of Psn9/Psn143
AP-1μSHE-11, Psn9/Psn143 has visible phenotype
AP-1μSHE-11/AP-1μSAE-10, Psn9/Psn143 has visible phenotype
AP-1μSHE-11, Psn9/Psn143 has some die during P-stage phenotype
AP-1μSHE-11 has tormogen cell | increased number | somatic clone phenotype, suppressible by SerRX106/DlRevF10
AP-1μSHE-11 has tormogen cell | increased number | somatic clone phenotype, suppressible by spdoG104
AP-1μSHE-11 has tormogen cell | increased number | somatic clone phenotype, non-suppressible by WASp3
AP-1μSHE-11 is an enhancer of eye phenotype of Psn9/Psn143
AP-1μSHE-11 is a suppressor of external sensory organ | somatic clone phenotype of WASp3
AP-1μSHE-11 is a suppressor of external sensory organ | somatic clone phenotype of spdoG104
AP-1μSHE-11 is a non-suppressor | somatic clone of external sensory organ phenotype of DlRevF10, SerRX106
AP-1μSHE-11, Psn9/Psn143 has wing vein phenotype
AP-1μSHE-11/AP-1μSAE-10, Psn9/Psn143 has wing vein phenotype
AP-1μSHE-11/AP-1μSAE-10, Psn9/Psn143 has wing phenotype
AP-1μSHE-11/AP-1μSAE-10, Psn9/Psn143 has microchaeta phenotype
A DlRevF10 SerRX106 double mutant background suppresses the extra socket cell phenotype seen in AP-47SHE-11 thorax clones, instead producing the external sensory cell loss and excess neurons seen in DlRevF10 SerRX106 double mutants.
AP-47SHE-11 suppresses the external sensory cell loss and excess neurons seen in WASp3 mutant thorax clones, instead producing the extra socket cell phenotype seen in AP-47SHE-11 mutants alone.
spdoG104 suppresses the extra socket cell phenotype seen in AP-47SHE-11 thorax clones, instead producing the external sensory cell loss and excessive neurons seen in spdoG104 mutants alone.
AP-47SHE-11 Psn9/Psn143 flies show wing vein thickening and low penetrance pupal lethality.
AP-47SAE-10/AP-47SHE-11 Psn9/Psn143 flies have dorsal and ventral wing notching, enhanced wing vein thickening and show loss of notal microchaetae.