A region of 37bp is deleted and replaced by 5bp (GTCGG). This results in a frameshift and premature translation termination. A protein of 682 amino acids is produced, the last 29 of which are unrelated to wild type ey sequence. Position of mutation on reference sequence inferred by FlyBase curator.
Deletion of sequences encoding amino acid residues 146-158, resulting in a predicted frameshift.
37 nucleotide deletion resulting in the deletion of amino acids 146 to 158 and a frameshift.
viable (with AP-1μEP1112)
AP-1μSHE-11 ddaC neuron clones within mosaic individuals do not present significant dendrite pruning defects at 16h after puparium formation, as compared to controls.
Eyes containing AP-47SHE-11 clones are rough.
Irregularly aligned photoreceptor cells are observed in AP-47SHE-11 eye disc clones.
11% of AP-47SHE-11 mutant adult sensory organ clones contain extra socket cells.
Homozygous AP-47SHE-11 mutant clones cells induced in third instar larval salivary gland cells either lack detectable glue granules or accumulate small granules in the cytoplasm. AP-47SHE-11 mutant cells also appear smaller than wild type. AP-47SHE-11/+ cells are of an intermediate size, suggesting that AP-47SHE-11 is dosage dependent.
The glue granules of AP-47SHE-11/AP-47EP1112 mutant third instar larvae are smaller than wild type, but larger than those seen in homozygous AP-47SHE-11 mutant larvae.
Salivary gland cell growth (which normally occurs in the third larval instar, starting at the distal end of the gland) is defective in AP-47EP1112/AP-47SHE-11 third instar larvae.
AP-1μSHE-11 is an enhancer of visible phenotype of Psn9/Psn143
AP-1μSHE-11, Psn9/Psn143 has visible phenotype
AP-1μSHE-11/AP-1μSAE-10, Psn9/Psn143 has visible phenotype
AP-1μSHE-11, Psn9/Psn143 has some die during P-stage phenotype
AP-1μSHE-11 has tormogen cell | supernumerary | somatic clone phenotype, suppressible by SerRX106/DlRevF10
AP-1μSHE-11 has tormogen cell | supernumerary | somatic clone phenotype, suppressible by spdoG104
AP-1μSHE-11 has tormogen cell | supernumerary | somatic clone phenotype, non-suppressible by WASp3
AP-1μSHE-11 is an enhancer of eye phenotype of Psn9/Psn143
AP-1μSHE-11 is a suppressor of external sensory organ | somatic clone phenotype of WASp3
AP-1μSHE-11 is a suppressor of external sensory organ | somatic clone phenotype of spdoG104
AP-1μSHE-11 is a non-suppressor | somatic clone of external sensory organ phenotype of DlRevF10, SerRX106
AP-1μSHE-11, Psn9/Psn143 has wing vein phenotype
AP-1μSHE-11/AP-1μSAE-10, Psn9/Psn143 has wing vein phenotype
AP-1μSHE-11/AP-1μSAE-10, Psn9/Psn143 has wing phenotype
AP-1μSHE-11/AP-1μSAE-10, Psn9/Psn143 has microchaeta phenotype
A DlRevF10 SerRX106 double mutant background suppresses the extra socket cell phenotype seen in AP-47SHE-11 thorax clones, instead producing the external sensory cell loss and excess neurons seen in DlRevF10 SerRX106 double mutants.
AP-47SHE-11 suppresses the external sensory cell loss and excess neurons seen in WASp3 mutant thorax clones, instead producing the extra socket cell phenotype seen in AP-47SHE-11 mutants alone.
spdoG104 suppresses the extra socket cell phenotype seen in AP-47SHE-11 thorax clones, instead producing the external sensory cell loss and excessive neurons seen in spdoG104 mutants alone.
AP-47SHE-11 Psn9/Psn143 flies show wing vein thickening and low penetrance pupal lethality.
AP-47SAE-10/AP-47SHE-11 Psn9/Psn143 flies have dorsal and ventral wing notching, enhanced wing vein thickening and show loss of notal microchaetae.