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General Information
Symbol
Dmel\stgEY12388
Species
D. melanogaster
Name
FlyBase ID
FBal0158600
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
stringEY12388
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{EPgy2}stgEY12388
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Wings of flies heterozygous for stgEY12388 are found to be slightly smaller than that of wild-type flies.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Phenotype Manifest In
Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

One copy of stgEY12388 partially suppresses the segment gap phenotype seen in the abdomens of mir-965KO1/mir-965KO2 mutant flies. The asynchronous histoblast division and reduction in histoblast migration rate are also suppressed.

stgEY12388/+ suppresses the rough-eye phenotype and increases the number of normal photoreceptors per ommatidium in flies expressing tefudsRNA.Scer\UAS under the control of Scer\GAL4GMR.PU. Significantly reduced severity of progressive neurodegeneration is also observed in these animals.

Expression of tefudsRNA.Scer\UAS under the control of Scer\GAL4elav.PU results in increased levels of photoreceptor cell division in third instar larval eye discs, which is suppressed by stgEY12388/+.

Xenogenetic Interactions
Statement
Reference

stgEY12388 appears to extend the lifespan of a subset of Scer\GAL4D42>Hsap\TARDBPScer\UAS.cHa flies. Further analysis reveals that the lifespan extension is restricted to female flies.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (5)