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General Information
Symbol
Dmel\rtdsRNA.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0158710
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat of nucleotides 67-566 of the coding sequence of rt.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Adults expressing rtdsRNA.Scer\UAS under the control of Scer\GAL4Act5C.PU have significantly decreased climbing ability compared to control flies.

Expression of rtdsRNA.Scer\UAS under the control of Scer\GAL4Act5C.PU results in some lethality, which increases as the temperature is increased.

Expression of rtdsRNA.Scer\UAS under the control of Scer\GAL4Act5C.PU, but not Scer\GAL4elav.PU or Scer\GAL4repo, results in a significant decrease in the median lifespan of flies compared to controls.

At 25oC, flies expressing rtdsRNA.Scer\UAS under the control of Scer\GAL4Act5C.PHb have a viability of 19%, while at 28oC, the viability is 0%. Adult escapers expressing rtdsRNA.Scer\UAS under the control of Scer\GAL4Act5C.PHb show a clockwise twisted abdomen phenotype (the phenotype is seen in both males and females).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference
Other
Phenotype Manifest In
Enhancer of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The penetrance of the blistered wing phenotype caused by expression of DgdsRNA.Scer\UAS.cUa under the control of Scer\GAL4en-e16E is significantly enhanced by co-expression of rtdsRNA.Scer\UAS at 28[o]C.

Animals expressing both Pomt2dsRNA.Scer\UAS and rtdsRNA.Scer\UAS under the control of Scer\GAL4Act5C.PHb show complete lethality.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
rtdsRNA.Scer\UAS
rtdsRNA.UAS
Name Synonyms
Secondary FlyBase IDs
    References (2)