FB2025_01 , released February 20, 2025
Allele: Dmel\nae04385
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General Information
Symbol
Dmel\nae04385
Species
D. melanogaster
Name
FlyBase ID
FBal0158902
Feature type
allele
Associated gene
Dmel\na
Associated Insertion(s)
PBac{RB}nae04385
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
piggyBac activity
(Bloomington Drosophila Stock Center, 2004.11.6)
Progenitor genotype
Associated Insertion(s)
PBac{RB}nae04385
Cytology
Description
Allele components
Component
Use(s)
Inserted element
PBac{RB}
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant flies show hypersensitivity to halothane when assayed for the ability of anesthetics to interfere with reactive climbing. Mutant flies elute more slowly than control flies in an inebriometer test of postural control in response to halothane but not to enflurane.

      Mutants have a cylindrically shaped abdomen and hesitant walking mode.

      (Humphrey et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      nae04385/+;; unc79x25/+ flies do not exhibit strong behavioural rhythmicity deficits in DD conditions (constant darkness) compared to single heterozygotes.

      nae04385/+;; unc80x42/+ flies do not exhibit strong behavioural rhythmicity deficits in DD conditions (constant darkness) compared to single heterozygotes.

      (Lear et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      e04385
      (Humphrey et al., 2007)
      nae04385
      (Lear et al., 2013)
      na[e04385]
      (Lear et al., 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)