FB2025_01 , released February 20, 2025
Allele: Dmel\TFAMc01716
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General Information
Symbol
Dmel\TFAMc01716
Species
D. melanogaster
Name
FlyBase ID
FBal0159689
Feature type
allele
Associated gene
Dmel\TFAM
Associated Insertion(s)
PBac{PB}TFAMc01716
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
piggyBac activity
(Bloomington Drosophila Stock Center, 2004.11.6)
Progenitor genotype
Associated Insertion(s)
PBac{PB}TFAMc01716
Cytology
Description
Allele components
Component
Use(s)
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of TFAMUAS.cCa under the control of Scer\GAL4nSyb.PS in the TFAMc01716/+ heterozygous mutant background leads to climbing and wing inflation defects when compared to controls.

      (Hunt et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      Scer\GAL4nSyb.PS, TFAMUAS.cCa, TFAMc01716 has wing phenotype, enhanceable by L2HGDHHMC03444, Scer\GAL4nSyb.PS

      (Hunt et al., 2019)
      Suppressed by
      Statement
      Reference

      Scer\GAL4nSyb.PS, TFAMUAS.cCa, TFAMc01716 has wing phenotype, suppressible by L2HGDHUAS.cLa, Scer\GAL4nSyb.PS

      (Hunt et al., 2019)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of L2HGDHHMC03444 under the control of Scer\GAL4nSyb.PS exacerbates climbing and wing inflation defects exhibited as a result of expression of TFAMUAS.cCa under the control of Scer\GAL4nSyb.PS in the TFAMc01716/+ heterozygous mutant background.

      Expression of L2HGDHUAS.cLa under the control of Scer\GAL4nSyb.PS suppresses climbing and wing inflation defects exhibited as a result of expression of TFAMUAS.cCa under the control of Scer\GAL4nSyb.PS in the TFAMc01716/+ heterozygous mutant background.

      (Hunt et al., 2019)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      TFAMc01716
      (Bateman, 2022, Hunt et al., 2019, Duncan et al., 2018)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)