FlyBase Allele Report: Dmel\Spn88Ea[c01214]

General Information

Symbol

Dmel\Spn88Ea^c01214

Species

D. melanogaster

Name

FlyBase ID

FBal0159736

Feature type

allele

Associated gene

Dmel\Spn88Ea

Associated Insertion(s)

PBac{PB}Spn88Ea^c01214

Carried in Construct

Also Known As

spn5^c01214

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

piggyBac activity

Nature of the Allele

Allele class

Mutagen

piggyBac activity

(Bloomington Drosophila Stock Center, 2004.11.6)

Progenitor genotype

Associated Insertion(s)

PBac{PB}Spn88Ea^c01214

Cytology

Description

Allele components

Component

Use(s)

Also carries

FRT

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:15,205,166..15,205,166 [+]

(Ahmad et al., 2009, Bloomington Drosophila Stock Center, 2004.11.6)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates carcinoma

modeled by scrib¹

(Katsukawa et al., 2018)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Spn5^c01214 and Spn5^c01214/Df(3R)ED5664 mutant larvae exhibit spontaneous melanization.

(Ahmad et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Hsap\CHMP2B^Intron5.UAS, Scer\GAL4^GMR.PF, Spn88Ea^c01214/Spn5[+] has increased cell death phenotype, suppressible by Spn88Ea^UAS.cAa, Scer\GAL4^GMR.PF

(Ahmad et al., 2009)

Enhancer of

Statement

Reference

Spn88Ea^c01214, Scer\GAL4^GMR.PF is an enhancer of increased cell death phenotype of Hsap\CHMP2B^Intron5.UAS, Scer\GAL4^GMR.PF

(Ahmad et al., 2009)

Spn88Ea^c01214/Spn5[+], Scer\GAL4^GMR.PF is an enhancer of increased cell death phenotype of Hsap\CHMP2B^Intron5.UAS, Scer\GAL4^GMR.PF

(Ahmad et al., 2009)

Phenotype Manifest In

Suppressed by

Statement

Reference

Hsap\CHMP2B^Intron5.UAS, Scer\GAL4^GMR.PF, Spn88Ea^c01214/Spn5[+] has eye phenotype, suppressible by Spn88Ea^UAS.cAa, Scer\GAL4^GMR.PF

(Ahmad et al., 2009)

Enhancer of

Statement

Reference

Spn88Ea^c01214, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Hsap\CHMP2B^Intron5.UAS, Scer\GAL4^GMR.PF

(Ahmad et al., 2009)

Spn88Ea^c01214/Spn5[+], Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Hsap\CHMP2B^Intron5.UAS, Scer\GAL4^GMR.PF

(Ahmad et al., 2009)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Spn5^c01214 significantly enhances the Hsap\CHMP2B^{Intron5.Scer\UAS} Scer\GAL4^GMR.PF eye phenotype.

Expression of Spn5^Scer\UAS.cAa in the eye under the control of Scer\GAL4^GMR.PF completely suppresses the enhancement effect of Spn5^c01214/+ on the Hsap\CHMP2B^{Intron5.Scer\UAS} locus.

(Ahmad et al., 2009)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

10425

w¹¹¹⁸; PBac{PB}Spn88Ea^c01214/TM6B, Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Spn5^c01214

(Katsukawa et al., 2018)

Spn88Ea^c01214

(Katsukawa et al., 2018)

spn5^c01214

(Ahmad et al., 2009)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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