Allele Dmel\Oseg1¹⁷⁹

General Information
Symbol	Dmel\Oseg1¹⁷⁹	Species	D. melanogaster
Name		FlyBase ID	FBal0160077
Feature type	allele	Associated gene	Dmel\Oseg1

Map ( GBrowse )
Allele class
Mutagen
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References point mutation 3L:8,403,713..8,403,713 reported_pr_change=E243@ evidence=experimental na_change=G8403713T pr_change=E243@\|Oseg1-PA reported_na_change=G881A (Avidor-Reiss et al., 2004, Avidor-Reiss, 2006.1.9)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Amino acid replacement: E243@. (Avidor-Reiss, 2006.1.9) Nucleotide substitution: G881A. FlyBase curator comment: Authors state amino acid replacement to be E727, however Avidor-Reiss, 2006.1.9, personal communication to FlyBase corrects this to E243. (Avidor-Reiss et al., 2004)
Cytology
Phenotypic Data
Phenotypic Class
	neurophysiology defective (Avidor-Reiss et al., 2004)
Phenotype Manifest In
	mechanosensory neuron (Avidor-Reiss et al., 2004) trichogen cell (Avidor-Reiss et al., 2004)
Detailed Description
	Statement Reference Mutant animals exhibit defects in the sensory cilium. Mutants have normal inner segments, an intact rootlet, basal bodies and connecting cilia, However, dramatic defects are seen in the outer segment morphology, in both mechano- and chemosensory chaetae. Mutant animals exhibit reduced mechanoreceptor currents and strongly attenuated chemosensory responses to sucrose. Their transepithelial potentials are normal. (Avidor-Reiss et al., 2004)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	"Amino acid replacement: E243@." was stated as revision. (Avidor-Reiss, 2006.1.9)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Oseg1¹⁷⁹
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Avidor-Reiss et al., 2004, Cell 117(4): 527--539 Decoding cilia function; defining specialized genes required for compartmentalized cilia biogenesis. [FBrf0174448]
Personal communication to FlyBase	Avidor-Reiss, 2006.1.9, Question about Oseg1 alleles. Question about Oseg1 alleles. [FBrf0191624]

Allele Dmel\Oseg1179

Allele Dmel\Oseg1¹⁷⁹