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General Information
Symbol
Dmel\Oseg1179
Species
D. melanogaster
Name
FlyBase ID
FBal0160077
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    point mutation
    Nucleotide change:

    G8410613T

    Reported nucleotide change:

    G881A

    Amino acid change:

    E243term | Oseg1-PA; E243term | Oseg1-PB

    Reported amino acid change:

    E243term

    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference

    Revision of data reported in FBrf0174448.

    Amino acid replacement: E243term.

    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Mutant animals exhibit defects in the sensory cilium. Mutants have normal inner segments, an intact rootlet, basal bodies and connecting cilia, However, dramatic defects are seen in the outer segment morphology, in both mechano- and chemosensory chaetae. Mutant animals exhibit reduced mechanoreceptor currents and strongly attenuated chemosensory responses to sucrose. Their transepithelial potentials are normal.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    Comments
    Comments

    "Amino acid replacement: E243@." was stated as revision.

    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Oseg1179
    Name Synonyms
    Secondary FlyBase IDs
      References (3)