|Feature type||allele||Associated gene||Dmel\Lnk|
|Map ( GBrowse )||
|Allele class||amorphic allele - genetic evidence|
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
|All updates||Click here to see a list of all updates to this record from FB2010_08 and on.|
|Nature of the Allele|
|Mutations Mapped to the Genome|
transposable element insertion site
|Associated Sequence Data|
|Nature of the lesion|
Insertion within the first intron.
|Caused by insertion|
|Phenotype Manifest In|
Egg chambers arrest in early vitellogenesis in mutant females.
Homozygotes show a 20% reduction in wing area and a 42% reduction in body mass compared to wild-type controls. The mean number of cells per wing and the mean cell size in the wing are both reduced in the mutant flies. A significant increase in both median and maximum lifespan is seen in both homozygous males and females compared to controls. Homozygous females produce significantly fewer eggs compared to wild-type females. Wild-type females mated to homozygous males produce normal numbers of offspring. Lnk[d07478]/Lnk[Del29] animals show a 16% reduction in wing area and a 34% reduction in body mass compared to wild-type controls.
Body length is decreased by 11% compared to controls in homozygous third instar larvae and body weight is decreased by 21% in homozygous adults. Homozygous adults have wings that are reduced in size due to controls, due to a decrease both in the size and number of cells. Total triglycerides are increased by 92% in the fat bodies of homozygous adults compared to those of control wild-type animals. Hemolymph trehalose levels are increased by 37% in homozygous flies compared to controls. Whole body trehalose and total sugar levels are increased by 102% and 85% respectively in homozygous flies compared to controls. Homozygous and Lnk[d07478]/Lnk[f02642] files show increased survival under starvation conditions compared to wild type. Homozygotes show an increase in lifespan compared to control; the median lifespan is increased by 14% in male and 33% in female flies, while the maximal lifespan is increased by 14% in male and 15% in female flies. Homozygotes show increased resistance to paraquat compared to wild type.
|Phenotype Manifest In|
Lnkd07478/LnkCR642 is a suppressor of dorsal appendage | maternal effect phenotype of spn-A093A/spn-A1
The ventralisation phenotype seen in eggs laid by spn-B[BU] females is suppressed if the females are also mutant for Lnk[CR642]/Lnk[d07478]. The ventralisation phenotype seen in eggs laid by spn-A[093A]/spn-A females is suppressed if the females are also mutant for Lnk[CR642]/Lnk[d07478].
|Complementation & Rescue Data|
|Stocks ( 2 )|
|Notes on Origin|
|External Crossreferences & Linkouts|
|Synonyms & Secondary IDs ( 3 )|
|Secondary FlyBase IDs|
|References ( 6 )|
|Personal communication to FlyBase|