Allele Dmel\GluRIID^e01443

General Information
Symbol	Dmel\GluRIID^e01443	Species	D. melanogaster
Name		FlyBase ID	FBal0160268
Feature type	allele	Associated gene	Dmel\GluRIID

Map ( GBrowse )	Untitled Document
Allele class	loss of function allele
Mutagen	piggyBac transposase
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class	loss of function allele (Qin et al., 2005)
Mutagen	piggyBac transposase (Bloomington Drosophila Stock Center, 2004.11.6)
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site 3R:16,476,389..16,476,389 (Bloomington Drosophila Stock Center, 2004.11.6, Qin et al., 2005)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference PBac{RB} inserted into intron 6 of KaiRIA. (Qin et al., 2005)
Caused by insertion	PBac{RB}GluRIID^e01443 (Bloomington Drosophila Stock Center, 2004.11.6, Qin et al., 2005)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| recessive (Qin et al., 2005) paralytic (Qin et al., 2005)
Phenotype Manifest In
	neuromuscular junction (Qin et al., 2005)
Detailed Description
	Statement Reference Mutant embryos show no coordinated movements and do not hatch, despite being apparently fully developed. Neuromuscular junction anatomy is grossly normal. GluRIIC staining shows the nmjs to be devoid of GluRIIC. (Qin et al., 2005)
External Data
Linkouts
Interactions
Phenotypic Class
NOT suppressed by
Statement Reference GluRIID^e01443 has lethal \| recessive phenotype, non-suppressible by GluRIIE^g.Scer\UAS/Scer\GAL4^unspecified (Qin et al., 2005)
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescued by	GluRIID^e01443 is rescued by Scer\GAL4^Mhc.PW/GluRIID^g.Scer\UAS (Qin et al., 2005)
Partially rescued by	GluRIID^e01443 is partially rescued by GluRIID^g.Scer\UAS/Scer\GAL4[-] (Qin et al., 2005)
Comments
Stocks ( 2 )
Bloomington	17952 w¹¹¹⁸; PBac{RB}GluRIID^e01443/TM6B, Tb¹
Harvard	- PBac{RB}GluRIID^e01443
Notes on Origin
Discoverer

Comments
	Complements: GluRIIE^E1. (Qin et al., 2005)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	GluRIID^e01443 (Qin et al., 2005, ) KaiRIA^e01443 (Christensen et al., 2008.4.15, )
Name Synonym
Secondary FlyBase IDs

References ( 5 )
Research paper	Featherstone et al., 2005, J. Neurosci. 25(12): 3199--3208 An essential Drosophila glutamate receptor subunit that functions in both central neuropil and neuromuscular junction. [FBrf0184094] Qin et al., 2005, J. Neurosci. 25(12): 3209--3218 Four different subunits are essential for expressing the synaptic glutamate receptor at neuromuscular junctions of Drosophila. [FBrf0184095]
Personal communication to FlyBase	Christensen et al., 2008.4.15, Isolation and characterization of Df(3R)BSC488. Isolation and characterization of Df(3R)BSC488. [FBrf0204516] Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file) Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797]

Allele Dmel\GluRIIDe01443

Allele Dmel\GluRIID^e01443