Allele Dmel\dysc^c03838

General Information
Symbol	Dmel\dysc^c03838	Species	D. melanogaster
Name		FlyBase ID	FBal0160893
Feature type	allele	Associated gene	Dmel\dysc

Map ( GBrowse )	Untitled Document
Allele class	amorphic allele - molecular evidence
Mutagen	piggyBac transposase
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class	amorphic allele - molecular evidence (Jepson et al., 2012)
Mutagen	piggyBac transposase (Bloomington Drosophila Stock Center, 2004.11.6)
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site 3L:13,879,409..13,879,409 (Bloomington Drosophila Stock Center, 2004.11.6)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference dysc[c03838] renders expression of all dysc isoforms undetectable. (Jepson et al., 2012)
Caused by insertion	PBac{PB}dysc^c03838 (Bloomington Drosophila Stock Center, 2004.11.6)
Cytology
Phenotypic Data
Phenotypic Class
	fertile (Bloomington Drosophila Stock Center, 2004.11.6) locomotor rhythm defective (with Df(3L)BSC614) (Jepson et al., 2012) locomotor rhythm defective (with dysc^c05107) (Jepson et al., 2012) locomotor rhythm defective (with dysc^s168) (Jepson et al., 2012) locomotor rhythm defective \| recessive (Jepson et al., 2012) viable (Bloomington Drosophila Stock Center, 2004.11.6)
Phenotype Manifest In

Detailed Description
	Statement Reference Most dysc[c03838] homozygotes and dysc[c03838]/Df(3L)BSC614 animals display arrhythmic locomotor patterns in constant dark conditions. In contrast to wild type flies, dysc[c03838] homozygotes do not exhibit anticipation of lights-on in 12 h light:dark conditions, while anticipation of lights-off is maintained. Overall daytime and nighttime activity is greater in these mutants compared to wild type in these conditions. dysc[s168]/dysc[c03838] animals display arrhythmic locomotor patterns in constant dark conditions. dysc[c03838]/dysc[c05107] animals display arrhythmic locomotor patterns in constant dark conditions. (Jepson et al., 2012)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescued by	dysc^s168/dysc^c03838 is rescued by dysc^Scer\UAS.g/Scer\GAL4^C164 (Jepson et al., 2012) dysc^s168/dysc^c03838 is rescued by dysc^Scer\UAS.g/Scer\GAL4^dysc.PJ (Jepson et al., 2012) dysc^s168/dysc^c03838 is rescued by dysc^Scer\UAS.g/Scer\GAL4^elav.PU (Jepson et al., 2012)
Not rescued by	dysc^s168/dysc^c03838 is not rescued by dysc^Scer\UAS.g/Scer\GAL4^c061 (Jepson et al., 2012) dysc^s168/dysc^c03838 is not rescued by dysc^Scer\UAS.g/Scer\GAL4^c107 (Jepson et al., 2012) dysc^s168/dysc^c03838 is not rescued by dysc^Scer\UAS.g/Scer\GAL4^c819 (Jepson et al., 2012) dysc^s168/dysc^c03838 is not rescued by dysc^Scer\UAS.g/Scer\GAL4^dimm-929 (Jepson et al., 2012) dysc^s168/dysc^c03838 is not rescued by dysc^Scer\UAS.g/Scer\GAL4^ey-OK107 (Jepson et al., 2012) dysc^s168/dysc^c03838 is not rescued by dysc^Scer\UAS.g/Scer\GAL4^how-24B/Scer\GAL4^how-24B (Jepson et al., 2012) dysc^s168/dysc^c03838 is not rescued by dysc^Scer\UAS.g/Scer\GAL4^Ilp2.PR (Jepson et al., 2012) dysc^s168/dysc^c03838 is not rescued by dysc^Scer\UAS.g/Scer\GAL4^P2.4.Pdf (Jepson et al., 2012) dysc^s168/dysc^c03838 is not rescued by dysc^Scer\UAS.g/Scer\GAL4^repo.PU (Jepson et al., 2012) dysc^s168/dysc^c03838 is not rescued by dysc^Scer\UAS.g/Scer\GAL4^Tab2-201Y (Jepson et al., 2012) dysc^s168/dysc^c03838 is not rescued by dysc^Scer\UAS.g/Scer\GAL4^tim.PE (Jepson et al., 2012) dysc^s168/dysc^c03838 is not rescued by dysc^Scer\UAS.g/Scer\GAL4^VGlut-OK371 (Jepson et al., 2012) dysc^s168/dysc^c03838 is not rescued by Scer\GAL4^elav.PU/dysc^Scer\UAS.f (Jepson et al., 2012)
Comments	Scer\GAL4[elav.PU]-, Scer\GAL4[dysc.PJ]-, or Scer\GAL4[C164]-mediated expression of dysc[Scer\UAS.g] rescues the locomotor rhythm defects of dysc[c03838]/dysc[s168] animals. Scer\GAL4[elav.PU]-mediated expression of dysc[Scer\UAS.f] does not rescue the locomotor rhythm defects of dysc[c03838]/dysc[s168] animals. (Jepson et al., 2012)
Stocks ( 2 )
Bloomington	11313 w¹¹¹⁸; PBac{PB}dysc^c03838
Harvard	- PBac{PB}dysc^c03838
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	CG8760^c03838 CG34400^c03838 CG43749^c03838 dysc^c03838 (Jepson et al., 2012)
Name Synonym
Secondary FlyBase IDs

References ( 3 )
Research paper	Jepson et al., 2012, PLoS Genet. 8(4): e1002671 dyschronic, a Drosophila Homolog of a Deaf-Blindness Gene, Regulates Circadian Output and Slowpoke Channels. [FBrf0218124]
Personal communication to FlyBase	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file) Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797]

Allele Dmel\dyscc03838

Allele Dmel\dysc^c03838