FB2025_01 , released February 20, 2025
Allele: Dmel\BI-1EY03662
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General Information
Symbol
Dmel\BI-1EY03662
Species
D. melanogaster
Name
FlyBase ID
FBal0161063
Feature type
allele
Associated gene
Dmel\BI-1
Associated Insertion(s)
P{EPgy2}BI-1EY03662
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EPgy2}BI-1EY03662
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EPgy2}
Regulatory region(s)
UASp
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      At 14 hours after puparium formation, pupae expressing BI-1EY03662 under the control of Scer\GAL4da.G32 exhibit delayed morphological and actin cytoskeletal changes associated with degradation of salivary gland cells, compared to controls. This is reflected in an attenuated redcution in cell size.

      Larvae expressing BI-1EY03662 under the control of Scer\GAL4da.G32 show a marked delay in the accumulation of lysosomes in the fat body under fasting conditions, compared to controls.

      (Castillo et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      BI-1EY03662
      CG7188EY03662
      dBI-1EY03662
      (Castillo et al., 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)