Open Close
General Information
Symbol
Dmel\crym
Species
D. melanogaster
Name
FlyBase ID
FBal0175714
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    point mutation
    Nucleotide change:

    C19215303T

    Amino acid change:

    R524term | cry-PA

    Comment:

    crym is reported as a premature stop codon that truncates the last 19 amino acids of cry.

    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference

    Premature stop codon that truncates the last 19 amino acids.

    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Mutant flies remain rhythmic in constant 3000-lux light. Mutant flies show changes in circadian behavioural phase in response to brief pulses of illumination at different times of the night; they show phase delays in the early night and phase advances in the late night. The magnitude of these phase changes is reduced compared to that seen in wild-type flies when the light intensity during the day is 1000 lux and the light pulse during the night is 3000 lux, but when the light intensity during the day is 25 lux and the light pulse during the night is 3000 lux the magnitude of the phase changes in the mutant flies is almost as robust as that in wild-type flies.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Fails to complement
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (2)