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General Information
Symbol
Dmel\Hr78dsRNA.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0176114
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Construct contains two overlapping regions of Hr78 separated by a 100 bp spacer; one region is an inverted repeat of the last 1004 bp of the Hr78 gene. The Hr78 sequences are expressed under the control of UASt regulatory sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Hr78dsRNA.Scer\UAS driven by the constitutively expressed Scer\GAL4da.G32 results in 81% of larvae examined displaying tracheal defects, including necrosis. The same phenotype is seen when Hr78dsRNA.Scer\UAS expression is driven by Scer\GAL4btl.PS, a tracheal specific driver, although only 13% of larvae are affected. Expression of Hr78dsRNA.Scer\UAS driven by Scer\GAL4Dll-md23 does not result in tracheal defects.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Used to study the phenotypic consequences of dsRNA interference (RNAi) of the Hr78 gene.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Hr78dsRNA.Scer\UAS
Hr78dsRNA.UAS
Name Synonyms
Secondary FlyBase IDs
    References (1)