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General Information
Symbol
Dmel\sdΔ200.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0178078
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A cDNA fragment corresponding to a truncated form of sd (missing the first 200 amino acid residues) is expressed under the control of UASt regulatory sequences. The deletion removes all of the sd TEA domain.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of sdΔ200.Scer\UAS under the control of Scer\GAL4ptc-559.1 results in a protruding eye phenotype. Eye bristles are duplicated or missing and can have altered morphology, and ommatidia may have bristles at four of their vertices. Fusion of ommatidia is also seen and an ectopic cluster of cells is seen between the lamina and ommatidia that coincides with the eye protrusion.

Expression of sdΔ200.Scer\UAS under the control of Scer\GAL4ptc-559.1 occasionally results in leg duplications. Loss of wing tissue and wing bristles is also seen in these flies.

Expression of sdΔ200.Scer\UAS under the control of Scer\GAL4ptc-559.1 results in an increase in cell death only along the anterior/posterior boundary of the wing pouch. There is also increased cell death in the leg imaginal disc, and the leg disc may be duplicated.

Expression of sdΔ200.Scer\UAS, driven by Scer\GAL4vg.boundary, leads to an enhancement of the wing phenotypes seen in sdETX4 and sd58d mutants. Overexpression of sdΔ200.Scer\UAS driven by Scer\GAL4vg.boundary leads to a defective wing phenotype in wild-type flies.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The defective wing phenotype seen when sdΔ200.Scer\UAS is expressed under control of Scer\GAL4vg.boundary in sdETX4 and sd58d mutants is alleviated when vgScer\UAS.cKa is overexpressed.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
sdΔ200.Scer\UAS
sdΔ200.UAS
Name Synonyms
Secondary FlyBase IDs
    References (2)