FB2025_01 , released February 20, 2025
Allele: Dmel\org-1UAS.cPa
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General Information
Symbol
Dmel\org-1UAS.cPa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Porsch
FlyBase ID
FBal0178559
Feature type
allele
Associated gene
Dmel\org-1
Associated Insertion(s)
Carried in Construct
P{UAS-org-1.P}
Also Known As
UAS-org-1
Key Links
Transgenic product class
wild_type
(Porsch et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Porsch et al., 2005)
Mutagen
in vitro construct
(Porsch et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-org-1.P}
Cytology
Description

UASt sequences drive expression of org-1.

(Porsch et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
org-1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When org-1Scer\UAS.cPa is driven by Scer\GAL4dpp.blk1, mutant antennae are defective. The third antennal segment contains ectopic bristles at its distal part. The arista is transformed into tarsal structures with a claw at the distal end. Legs are also defective - distal leg segments are extremely compressed and fused in mutants. An increase in ommatidial number by more than 15% is seen mutant eyes. When org-1Scer\UAS.cPa is driven by Scer\GAL4GMR.PF, disruptions of the regular ommatidial arrangement is seen in the eye. Also the eye bristles are largely missing.

      (Porsch et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      org-1Scer\UAS.cPa
      org-1UAS.cPa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Porsch
      (Porsch et al., 2005)
      Secondary FlyBase IDs
        References (2)