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General Information
Symbol
Dmel\hpoUAS.cPa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Pantalacci
FlyBase ID
FBal0179449
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-hpo
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UASt sequences drive expression of hpo sequence.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Clones in the wing disc expressing hpoScer\UAS.cPa under the control of Scer\GAL4unspecified are very small in size and seem to have slightly reduced levels of apical F-actin. Expression of hpoScer\UAS.cPa under the control of Scer\GAL4hh-Gal4 from the early third larval instar onwards (the temperature sensitive Scer\GAL80ts.αTub84B allele is used to restrict expression before this stage) does not disrupt the apical F-actin network in the wing disc.
Overexpression of hpoScer\UAS.cPa in the developing eye, under the control of Scer\GAL4GMR.PF induces cell death.
Expression of hpoScer\UAS.cPa, in eye imaginal disc somatic clones results in cell cycle arrest before the second mitotic wave.
Scer\GAL4GMR.PF-driven hpoScer\UAS.cPa expression strongly induces apoptosis in the posterior part of the eye imaginal disc.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement
Reference
Other
Additional Comments
Genetic Interactions
Statement
Reference
Overexpression of hpoScer\UAS.cPa in the developing eye, under the control of Scer\GAL4GMR.PF induces cell death in ft8 mutant cells.
WGMR.PG-induced apoptosis is blocked in hpodsRNA.Scer\UAS mutant clones.
Scer\GAL4GMR.PF-driven hpoScer\UAS.cPa expression-induced apoptosis is largely unimpaired in sav3 mutant clones.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
hpoScer\UAS.cPa
hpoUAS.cPa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Pantalacci
Secondary FlyBase IDs
    References (10)