FB2025_05 , released December 11, 2025
Allele: Dmel\Tdp1G85
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General Information
Symbol
Dmel\Tdp1G85
Species
D. melanogaster
Name
FlyBase ID
FBal0179628
Feature type
allele
Associated gene
Dmel\Tdp1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Dunlop et al., 2004)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes die at late embryonic/early larval stages. Homozygous embryos do not show any disruption in epithelial structures at stages 10-11. Homozygous embryos show a defasciculation of axon bundles, both within the commissures and the longitudinals of the central nervous system.

      (Dunlop et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      gktG85/gktG85 ; crb2/+ embryos show a severe disruption in epithelial polarity at stage 11.

      (Dunlop et al., 2004)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Tdp1k00223

      (Dunlop et al., 2004)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Complements: Mad2. Complements: MadB1. Complements: CG3347KG05281.

      (Dunlop et al., 2004)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Tdp1G85
      gktG85
      Name Synonyms
      Secondary FlyBase IDs
        References (1)