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General Information
Symbol
Dmel\eygPxA1
Species
D. melanogaster
Name
FlyBase ID
FBal0179917
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Consists of a deletion that starts 23bp upstream of eyg and extends 11.8kb downstream of the gene. Contains two P{lacW} element insertions at bases -124 and -147 relative to the translation start of eyg and in the same orientation as the gene.

Insertion components
P{lacW}PxA1a
Product class / Tool use(s)
Encoded product / tool
P{lacW}PxA1b
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

eygPxA1 mutants suffer head loss, making this mutation lethal. There is also a severe groove on the thorax.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Other
Additional Comments
Genetic Interactions
Statement
Reference

Flies overexpressing DlScer\UAS.cDa under the control of Scer\GAL4ey.PH that are also eygPxA1/eygXE119 mutants have eyes that are reduced in size or completely lack eyes altogether.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescued by
Comments

One copy of eygScer\UAS.lune under the control of Scer\GAL4ey.PH rescues eygPxA1/eyg123M11 mutants to healthy adulthood with almost normal-sized eyes.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (3)