FB2025_01 , released February 20, 2025
Allele: Dmel\Tm1Su(flw)4
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General Information
Symbol
Dmel\Tm1Su(flw)4
Species
D. melanogaster
Name
FlyBase ID
FBal0181207
Feature type
allele
Associated gene
Dmel\Tm1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Vereshchagina et al., 2004)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous olfactory receptor neuron (ORN) clones show no defects in the axonal targeting pattern or number of Or59c-expressing ORNs.

      (Stephan et al., 2012)

      Heterozygous border follicle cell clusters have abnormal actin-rich protrusions.

      Homozygous border follicle cells show defects in migration.

      (Kim et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Tm1[+]/Tm1Su(flw)4 is a suppressor | partially of decreased size | adult stage phenotype of Scer\GAL4A9, ShrmA.UAS

      (Hildebrand et al., 2021)

      Tm1Su(flw)4 is a suppressor of lethal | male phenotype of flw6

      (Vereshchagina et al., 2004)

      Tm1Su(flw)4 is a suppressor of lethal | male phenotype of flwG0172

      (Vereshchagina et al., 2004)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Tm1[+]/Tm1Su(flw)4 is a suppressor | partially of wing phenotype of Scer\GAL4A9, ShrmA.UAS

      (Hildebrand et al., 2021)

      Tm1Su(flw)4 is a suppressor of wing phenotype of flw6

      (Vereshchagina et al., 2004)

      Tm1Su(flw)4 is a suppressor of wing phenotype of flwG0172

      (Vereshchagina et al., 2004)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of psidinScer\UAS.cKa under the control of Scer\GAL4slbo.2.6 in a Tm1Su(flw)4 heterozygous background results in border cell migration defects (49.1%).

      (Kim et al., 2011)

      The crumpled wing phenotype of flw6 and flwG0172 flies is fully rescued by Tm1Su(flw)4.

      (Vereshchagina et al., 2004)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Tm102299

      (Vereshchagina et al., 2004)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Selected as: a dominant extragenic suppressor of flw6.

      (Vereshchagina et al., 2004)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Tm1Su(flw)4
      (Hildebrand et al., 2021, Kim et al., 2011)
      tm1su(flw)4
      (Stephan et al., 2012)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)