FB2025_02 , released April 17, 2025
Allele: Dmel\TaceRNAi.UAS.cSa
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General Information
Symbol
Dmel\TaceRNAi.UAS.cSa
Species
D. melanogaster
Name
FlyBase ID
FBal0181316
Feature type
allele
Associated gene
Dmel\Tace
Associated Insertion(s)
Carried in Construct
P{UAS-Tace.RNAi.S}
Key Links
Transgenic product class
RNAi_reagent
(Sapir et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Sapir et al., 2005)
Mutagen
in vitro construct
(Sapir et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-Tace.RNAi.S}
Cytology
Description

UASt regulatory sequences drive expression of Tace sequences.

(Sapir et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Tace
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eye-antennal disc clones expressing TacedsRNA.Scer\UAS under the control of Scer\GAL4Act.PU do not show overgrowth compared with controls.

      (Chabu and Xu, 2014)

      When driven by Scer\GAL4Bx-MS1096 no detectable phenotypes are seen.

      (Sapir et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of TacedsRNA.Scer\UAS suppresses the small eye phenotype seen when egrScer\UAS.cIa is expressed under the control of Scer\GAL4GMR.PU.

      Expression of TacedsRNA.Scer\UAS enhances the hanging eye phenotype seen when egrScer\UAS.cIa and bskDN.Scer\UAS are co-expressed under the control of Scer\GAL4GMR.PU. The majority of these triple mutant animals die in late pupal stages and show a ring of necrotic tissue around the eyes.

      Expression of TacedsRNA.Scer\UAS suppresses the overgrowth seen in eye-antennal disc clones expressing Ras85DV12.Scer\UAS under the control of Scer\GAL4Act.PU. The phenotype is further suppressed when the adjacent cells are homozygous mutant for Tak11.

      (Chabu and Xu, 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      TaceRNAi.UAS.cSa
      TacedsRNA.Scer\UAS
      TacedsRNA.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (3)