FB2025_01 , released February 20, 2025
Allele: Dmel\TSG101f00976
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General Information
Symbol
Dmel\TSG101f00976
Species
D. melanogaster
Name
FlyBase ID
FBal0181319
Feature type
allele
Associated gene
Dmel\TSG101
Associated Insertion(s)
PBac{WH}TSG101f00976
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
piggyBac activity
(Gene Disruption Project members and Exelixis, 2005)
Progenitor genotype
Associated Insertion(s)
PBac{WH}TSG101f00976
Cytology
Description
Allele components
Component
Use(s)
Inserted element
PBac{WH}
Regulatory region(s)
UAS
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      A single copy of TSG101f00976 does not cause an eye phenotype.

      (Ahmad et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      TSG101[+]/TSG101f00976, Scer\GAL4GMR.PF is an enhancer of increased cell death phenotype of Hsap\CHMP2BIntron5.UAS, Scer\GAL4GMR.PF

      (Ahmad et al., 2009)
      Suppressor of
      Statement
      Reference

      TSG101[+]/TSG101f00976 is a suppressor of abnormal neurophysiology | third instar larval stage phenotype of sky1/sky2

      (Uytterhoeven et al., 2011)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      TSG101[+]/TSG101f00976, Scer\GAL4GMR.PF is an enhancer of eye phenotype of Hsap\CHMP2BIntron5.UAS, Scer\GAL4GMR.PF

      (Ahmad et al., 2009)
      Suppressor of
      Statement
      Reference

      TSG101[+]/TSG101f00976 is a suppressor of embryonic/larval neuromuscular junction phenotype of sky1/sky2

      (Uytterhoeven et al., 2011)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The increased excitatory junctional current (EJC) amplitude seen at the neuromuscular junction in sky1/sky2 third instar larvae is suppressed if the larvae are also heterozygous for TSG101f00976.

      (Uytterhoeven et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference

      A single copy of TSG101f00976 significantly enhances the Hsap\CHMP2BIntron5.Scer\UAS Scer\GAL4GMR.PF phenotype in 1-day-old flies.

      (Ahmad et al., 2009)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      TSG101f00976
      vps23f00976
      (Ahmad et al., 2009)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)