FB2022_03, released June 9, 2022

Allele: Dmel\Src42AS-527

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General Information
Symbol
Dmel\Src42AS-527
Species
D. melanogaster
Name
FlyBase ID
FBal0181435
Feature type
allele
Associated gene
Dmel\Src42A
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    point_mutation
    2R:6,011,040..6,011,040 [+]
    Nucleotide change:

    A6011040T

    Amino acid change:

    D370V | Src42A-PA; D1450V | Src42A-PB

    Reported amino acid change:

    D370V

    Comment:

    Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

    (Laberge et al., 2005)
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
         
        Progenitor genotype
        Cytology
        Nature of the lesion
        Statement
        Reference

        Amino acid replacement: D370V.

        (Laberge et al., 2005)
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        Src42AS-527 is an enhancer of eye phenotype of Ras85DV12.sev

        (Laberge et al., 2005)

        Src42AS-527 is an enhancer of ommatidium phenotype of Ras85DV12.sev

        (Laberge et al., 2005)
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Fails to complement

        Src42Aunspecified

        (Tateno et al., 2000)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        S-527
        (Tateno et al., 2000)
        Src42AS-527
        Name Synonyms
        Secondary FlyBase IDs
          References (2)