FB2021_01, released Feb 18, 2021

Allele: Scer\GAL4TrpA1.PR

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General Information
Symbol
Scer\GAL4TrpA1.PR
Species
S. cerevisiae
Name
Transient receptor potential A1 promoter construct of Rosenzweig
FlyBase ID
FBal0181633
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{TrpA1-GAL4.R}
Also Known As
trpA1-Gal4
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct - regulatory fusion
(Rosenzweig et al., 2005)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Carried in construct
      P{TrpA1-GAL4.R}
      Cytology
      Nature of the lesion
      Statement
      Reference

      33-1301bp upstream of the TrpA1 translational start codon are fused upstream of sequence encoding a GAL4 driver.

      (Rosenzweig et al., 2005)
      Allele components
      Product class / Tool use(s)
      Regulatory region(s)
      TrpA1
      Encoded product / tool
      GAL4
      Associated Sequence Features
      TrpA1_Gal4
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      larval stage
      embryonic/larval brain | restricted

      Comment: central brain

      (Bloomington Drosophila Stock Center, 2017)
      pharate adult stage P8 -- P9
      antennal olfactory receptor neuron of third segment of antenna
      (Kwon et al., 2010)
      antennal olfactory receptor neuron of second segment of antenna
      (Kwon et al., 2010)
      antennal olfactory receptor neuron | subset
      (Kwon et al., 2010)
      wandering third instar larval stage
      embryonic/larval corpus cardiacum innervating neuron
      (Rosenzweig et al., 2005)
      neuron | subset of embryonic/larval brain
      (Rosenzweig et al., 2005)
      thermosensory neuron
      (Rosenzweig et al., 2005)
      third instar larval stage
      thermosensory neuron
      (Kwon et al., 2008)
      Additional Information
      Statement
      Reference

      Scer\GAL4TrpA1.PR drives expression in the central brain in the pattern of the TrpA1 gene.

      (Bloomington Drosophila Stock Center, 2017)

      Drives expression in neuroendocrine cells of the corpus cardiacum; in TrpA1-expressing neurons in the brain, along with ~100 other brain neurons; in bipolar dendrite neurons; two pairs of thermosensory neurons in the larval head.

      (FlyBase Curators, 2017)

      Scer\GAL4TrpA1.PR drives expression in six antennal olfactory receptor neurons in the third segment of the antenna, and several in the second segment.

      (Kwon et al., 2010)

      Scer\GAL4TrpA1.PR drives expression in two to six neurons in the third antennal segment, and several in the second antennal segment.

      (Kwon et al., 2010)

      Scer\GAL4TrpA1.PR drives expression in two pairs of thermosensory neurons near the tip of the larval head.

      (Kwon et al., 2008)

      Scer\GAL4TrpA1.PR drives expression in TrpA1-expressing neurons in the larval brain, and in about 100-150 other cells in the larval brain. Scer\GAL4TrpA1.PR also drives expression in neuroendocrine cells of the corpus cardiacum

      (Rosenzweig et al., 2005)
       
      Marker for
      Reflects expression of
      TrpA1
      (Bloomington Drosophila Stock Center, 2017, Kwon et al., 2010, Kwon et al., 2008)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Scer\GAL4TrpA1.PR
      Name Synonyms
      Transient receptor potential A1 promoter construct of Rosenzweig
      (Rosenzweig et al., 2005)
      Secondary FlyBase IDs
        References (15)