Allele Dmel\GluRIIE^E1

General Information
Symbol	Dmel\GluRIIE^E1	Species	D. melanogaster
Name		FlyBase ID	FBal0183418
Feature type	allele	Associated gene	Dmel\GluRIIE

Allele class
Mutagen	Delta2-3
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	Delta2-3 (Qin et al., 2005)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	P{EP}EP28753 (Qin et al., 2005)
Nature of the lesion	Statement Reference Deletion of 1.2kb of genomic sequence from the insertion of P{EP}EP28753 into the GluRIIE coding region, removing the C-terminal part of GluRIIE including the last transmembrane domain (domain 4). (Qin et al., 2005)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| recessive (Qin et al., 2005) paralytic (Qin et al., 2005)
Phenotype Manifest In
	neuromuscular junction (Qin et al., 2005)
Detailed Description
	Statement Reference Mutant embryos show no coordinated movements and do not hatch, despite being apparently fully developed. Neuromuscular junction anatomy is grossly normal. GluRIIC staining shows the nmjs to be devoid of GluRIIC. (Qin et al., 2005)
External Data
Linkouts
Interactions
Phenotypic Class
NOT suppressed by
Statement Reference GluRIIE^E1 has lethal \| recessive phenotype, non-suppressible by Scer\GAL4^unspecified/GluRIID^g.Scer\UAS (Qin et al., 2005)
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescued by	GluRIIE^E1 is rescued by GluRIIE^g.Scer\UAS/Scer\GAL4^unspecified (Qin et al., 2005)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	GluRIIE^E1
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Qin et al., 2005, J. Neurosci. 25(12): 3209--3218 Four different subunits are essential for expressing the synaptic glutamate receptor at neuromuscular junctions of Drosophila. [FBrf0184095]

Allele Dmel\GluRIIEE1

Allele Dmel\GluRIIE^E1