Deletion of 1.2kb of genomic sequence from the insertion of P{EP}EP28753 into the GluRIIE coding region, removing the C-terminal part of GluRIIE including the last transmembrane domain (domain 4).
Mutant embryos show no coordinated movements and do not hatch, despite being apparently fully developed. Neuromuscular junction anatomy is grossly normal. GluRIIC staining shows the nmjs to be devoid of GluRIIC.