FB2021_01, released Feb 18, 2021

Allele: Dmel\GluRIIEE1

Open Close
General Information
Symbol
Dmel\GluRIIEE1
Species
D. melanogaster
Name
FlyBase ID
FBal0183418
Feature type
allele
Associated gene
Dmel\GluRIIE
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Qin et al., 2005)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      P{EP}EP28753
      (Qin et al., 2005)
      Cytology
      Nature of the lesion
      Statement
      Reference

      Deletion of 1.2kb of genomic sequence from the insertion of P{EP}EP28753 into the GluRIIE coding region, removing the C-terminal part of GluRIIE including the last transmembrane domain (domain 4).

      (Qin et al., 2005)
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant embryos show no coordinated movements and do not hatch, despite being apparently fully developed. Neuromuscular junction anatomy is grossly normal. GluRIIC staining shows the nmjs to be devoid of GluRIIC.

      (Qin et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      GluRIIEE1 is rescued by GluRIIE+tQa

      (Qin et al., 2005)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      GluRIIEE1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)