FB2025_01 , released February 20, 2025
Allele: Dmel\EndoGIe00915
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General Information
Symbol
Dmel\EndoGIe00915
Species
D. melanogaster
Name
FlyBase ID
FBal0185529
Feature type
allele
Associated gene
Dmel\EndoGI
Associated Insertion(s)
PBac{RB}EndoGIe00915
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
piggyBac activity
(Gene Disruption Project members and Exelixis, 2005)
Progenitor genotype
Associated Insertion(s)
PBac{RB}EndoGIe00915
Cytology
Description

Insertion in the 5' untranslated region.

(Temme et al., 2009)
Allele components
Component
Use(s)
Inserted element
PBac{RB}
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      No premature mitochondrial nucleoid elimination is observed in EndoGIe00915 mutant spermatids.

      (Deluca and O'Farrell, 2012)

      Homozygous males raised on rich medium are infertile when crossed with wild-type females.

      Homozygotes show lower viability than normal flies, dying during late development but at no specific stage, and their viability is strongly influenced by genetic background and diet (no homozygotes are recovered if the mutants are cultured on less rich medium).

      (Temme et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      It has not been possible to excise the insertion to demonstrate whether or not the lethality associated with the chromosome is caused by the insertion.

      (Temme et al., 2009)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CG4930e00915
      EndoGIe00915
      (Deluca and O'Farrell, 2012)
      cg4930e00915
      (Temme et al., 2009)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)