Allele Dmel\hec^f06077

General Information
Symbol	Dmel\hec^f06077	Species	D. melanogaster
Name		FlyBase ID	FBal0185625
Feature type	allele	Associated gene	Dmel\hec

Map ( GBrowse )	Untitled Document
Allele class
Mutagen	piggyBac transposase
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	piggyBac transposase (Gene Disruption Project members and Exelixis, 2005)
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site X:12,845,760..12,845,760 (Gene Disruption Project members and Exelixis, 2005)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	PBac{WH}hec^f06077 (Gene Disruption Project members and Exelixis, 2005)
Cytology
Phenotypic Data
Phenotypic Class
	mating behavior defective \| male limited (Li et al., 2011)
Phenotype Manifest In

Detailed Description
	Statement Reference There is a significant drop in the courtship index (CI, the fraction of time spent performing any of the steps of courtship) of mutant males. They are capable of all courtship steps, but perform them less frequently. Short-term locomotor activity is unaffected. The male courtship phenotype is still observed if mutants are deprived of visual input or paired with young/mature virgin females. Mutant males do not show increased male-male courtship. hec[f06077] male flies missing the third antennal segment show significantly reduced courtship compared to control males under red light. (Li et al., 2011)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement Reference hec^f06077 has mating behavior defective \| male limited phenotype, enhanceable by fru[+]/fru⁴ (Li et al., 2011)
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference When hec[f06077] is placed in a fru[4]/+ background, a significantly lower courtship index is observed in males than in the hec[f06077] males alone. (Li et al., 2011)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescued by	hec^f06077 is rescued by hec^Scer\UAS.cLa/Scer\GAL4^hec.PL (Li et al., 2011) hec^f06077 is rescued by Scer\GAL4^fru-GAL4/hec^Scer\UAS.cLa (Li et al., 2011)
Comments	Expression of hec[Scer\UAS.cLa] using Scer\GAL4[hec.PL] or Scer\GAL4[fru.P1.D] completely rescues the courtship phenotype of hec[f06077] males. Expression of hec[Scer\UAS.cLa] only in adult mature males using Scer\GAL4[hec.PL] or Scer\GAL4[fru.P1.D] together with the Scer\GAL80[ts.αTub84B] system completely rescues the courtship phenotype of hec[f06077] males. (Li et al., 2011)
Stocks ( 1 )
Harvard	- PBac{WH}hec^f06077
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	CG4395^f06077 (Li et al., 2011, ) hec^f06077 PBac4395^f06077 (Li et al., 2011) PBacCG4395^f06077 (Li et al., 2011)
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Li et al., 2011, PLoS ONE 6(11): e28269 The hector G-Protein Coupled Receptor Is Required in a Subset of fruitless Neurons for Male Courtship Behavior. [FBrf0216834]
Personal communication to FlyBase	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file) Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340]

Allele Dmel\hecf06077

Allele Dmel\hec^f06077