FlyBase Allele Report: Dmel\Atpα[DTS2R2]

General Information

Symbol

Dmel\Atpα^DTS2R2

Species

D. melanogaster

Name

FlyBase ID

FBal0188147

Feature type

allele

Associated gene

Dmel\Atpα

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

hypomorphic allele - molecular evidence

Mutagen

gamma ray

Nature of the Allele

Allele class

hypomorphic allele - molecular evidence

(Ashmore et al., 2009)

Mutagen

gamma ray

(Palladino et al., 2003)

Progenitor genotype

Atpα^DTS2

(Palladino et al., 2003)

Cytology

Description

Atpα protein expression levels are reduced in heterozygotes.

(Ashmore et al., 2009)

Atpα^DTS1R2 has a lesion that removes at least some of exon 12.

(Palladino et al., 2003)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

bang sensitive

(Palladino et al., 2003)

lethal - all die during embryonic stage

(Palladino et al., 2003)

lethal - all die during embryonic stage (with Atpα^01453a)

(Palladino et al., 2003)

lethal - all die during embryonic stage (with Atpα²²⁰⁶)

(Palladino et al., 2003)

lethal - all die during embryonic stage (with Atpα^DTS1)

(Palladino et al., 2003)

lethal - all die during embryonic stage (with Atpα^DTS1R1)

(Palladino et al., 2003)

lethal - all die during embryonic stage (with Atpα^DTS1R2)

(Palladino et al., 2003)

lethal - all die during embryonic stage (with Atpα^DTS2)

(Palladino et al., 2003)

lethal - all die during embryonic stage (with Atpα^DTS2R1)

(Palladino et al., 2003)

lethal - all die during embryonic stage (with Atpα^DTS2R3)

(Palladino et al., 2003)

lethal - all die during embryonic stage (with Atpα^H64)

(Palladino et al., 2003)

paralytic

(Palladino et al., 2003)

some die during embryonic stage

(Palladino et al., 2003)

some die during embryonic stage (with Atpα^01453a)

(Palladino et al., 2003)

some die during embryonic stage (with Atpα²²⁰⁶)

(Palladino et al., 2003)

some die during embryonic stage (with Atpα^DTS1)

(Palladino et al., 2003)

some die during embryonic stage (with Atpα^DTS1R1)

(Palladino et al., 2003)

some die during embryonic stage (with Atpα^DTS1R2)

(Palladino et al., 2003)

some die during embryonic stage (with Atpα^DTS2)

(Palladino et al., 2003)

some die during embryonic stage (with Atpα^DTS2R1)

(Palladino et al., 2003)

some die during embryonic stage (with Atpα^DTS2R3)

(Palladino et al., 2003)

some die during embryonic stage (with Atpα^H64)

(Palladino et al., 2003)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

Atpα^DTS1

(Palladino et al., 2003)

Atpα^DTS2

(Palladino et al., 2003)

Atpα^DTS2R1

(Palladino et al., 2003)

Atpα^DTS2R3

(Palladino et al., 2003)

Atpα^H64

(Palladino et al., 2003)

Atpα^DTS1R1

(Palladino et al., 2003)

Atpα^DTS1R2

(Palladino et al., 2003)

Atpα^01453a

(Palladino et al., 2003)

Atpα²²⁰⁶

(Palladino et al., 2003)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Revertant.

(Palladino et al., 2003)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

ATPalpha^DTS2R2

(Ashmore et al., 2009)

Atpα^DTS2R2

DTS2^R2

(Palladino et al., 2003)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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