FB2025_02 , released April 17, 2025
Allele: Dmel\reptunspecified
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General Information
Symbol
Dmel\reptunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0189630
Feature type
allele
Associated gene
Dmel\rept
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        The position effect variegation at the w locus caused by In(1)wm4h is significantly suppressed by reptunspecified/+.

        (Hanai et al., 2008)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhanced by
        Statement
        Reference

        reptunspecified has suppressor of variegation | dominant phenotype, enhanceable by CG8677[+]/CG86773602

        (Hanai et al., 2008)
        Enhancer of
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        reptunspecified is an enhancer of ommatidium | somatic clone phenotype of MycPL35

        (Bellosta et al., 2005)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        CG86773602/+ ; reptunspecified/+ double heterozygotes show a synergistic effect on the position effect variegation at the w locus caused by In(1)wm4h, showing strong suppression of position effect variegation.

        (Hanai et al., 2008)

        Heterozygosity for reptunspecified in dmPL35 eye somatic clones results in a slight decrease in the number and size of ommatidia compared to dmPL35 eye somatic clones. Heterozygosity for reptunspecified and pontunspecified in dmPL35 eye somatic clones results in a decrease in the number and size of ommatidia compared to dmPL35 eye somatic clones in a wild-type background and in reptunspecified or pontunspecified heterozygous backgrounds.

        (Bellosta et al., 2005)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        reptunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (3)