A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Allele Dmel\eygΔRED.Scer\UAS

General Information
SymbolDmel\eygΔRED.Scer\UASSpeciesD. melanogaster
NameFlyBase IDFBal0189688
Feature typealleleAssociated geneDmel\eyg
Allele classantimorphic allele - genetic evidence
Mutagenin vitro construct - deletion
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Description
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FB2013_03
FB2013_02
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Allele class
Mutagen
Mutations Mapped to the Genome
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ /
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GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
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Progenitor genotype
Nature of the lesion
Statement
Reference
Construct: The RED domain (amino acids 51-102) has been deleted.
Carried in construct
Cytology
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Statement
Reference
Unlike overexpression of wild-type eyg, expression of eygΔRED.Scer\UAS, under the control of Scer\GAL4dpp.blk1, does not cause extra ventral eye formation. Expression of eygΔRED.Scer\UAS in a eyg22-2/eygM3-12 background has a dominant-negative effect on the eye and thorax phenotype of these mutants.
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Statement
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Fails to rescue
Comments
Expression of the eygΔRED.Scer\UAS transgene, under the control of Scer\GAL4eyg-22-2, enhances the grooved thorax and reduced eye phenotype of eygM3-12/eyg22-2 mutants.
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Reported As
Symbol Synonym
eygΔRED.Scer\UAS
 
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Research paper
Yao and Sun, 2005, EMBO J. 24(14): 2602--2612
Eyg and Ey Pax proteins act by distinct transcriptional mechanisms in Drosophila development. [FBrf0187515]