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General Information
Symbol
Dmel\mblchst
Species
D. melanogaster
Name
chaste
FlyBase ID
FBal0190023
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference

    Insertion approximately 400bp upstream of mbl.

    Insertion components
    P{BmΔ-w}mblchst
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Mutant females show reduced mating success compared to control females. The level of courtship activity elicited in wild-type males by mutant females is comparable to that elicited by control females. The mutant females are approached by males, who attempt to copulate, but in most cases, without success. The mutant females show different behaviour in response to courting males compared to control females; although decamping is the most prevalent response pattern of the females in boht cases, the mutant females show flying and jumping significantly more often that wild-type females, in addition to decamping.

    mblchst in transheterozygous combination with mblchst-exC18, mblchst-exC67, mblchst-exC106, mblchst-exC71, mblchst-exC3, mblchst-exC24, mblchst-exC110, mblchst-exC45, mblk05507b, mblE27, mblE127, mblk07110 or mblk07103 shows reduced female sexual receptivity compared to controls.

    mblchst in transheterozygous combination with mblchst-r1, mblchst-exC1, mblchst-exC2, mblchst-exS5, mblchst-exS14, mblchst-exC16, mblchst-exS45, mblchst-exC100, mblchst-exC20, mblchst-exS31, mblchst-exS86, mblchst-exC92, mblchst-exC99, mblE2563-12 or mblPP2 shows normal female sexual receptivity.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    za has no affect on the sexual receptivity of homozygous mblchst females.

    za ; mblchst-exC3/mblchst and za ; mblchst-exC45/mblchst females show reduced sexual receptivity compared to controls.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer
    Comments
    Comments

    Precise excision of the insertion completely reverts the reduced mating success of mutant females.

    External Crossreferences and Linkouts ( 1 )
    Crossreferences
    GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
    Synonyms and Secondary IDs (4)
    Reported As
    Symbol Synonym
    chasteAB036794
    mblchst
    Name Synonyms
    chaste
    Secondary FlyBase IDs
      References (2)