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General Information
Symbol
Dmel\Traf6EP1516
Species
D. melanogaster
Name
FlyBase ID
FBal0190077
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
EP(X)1516
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    transposable element insertion site
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference

    A P{EP} element is inserted in the 5' flanking region of Traf2.

    Insertion components
    P{EP}GIIIspla2EP1516
    Product class / Tool use(s)
    Encoded product / tool
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Overexpression of Traf2EP1516 under the regulation of Scer\GAL4ap-md544 has no effect on thorax closure.

    Expression of Traf2EP1516 under the control of Scer\GAL4GMR.PF does not affect eye development.

    The eye imaginal discs from transgenic flies overexpressing Traf2EP1516 under the control of Scer\GAL4GMR.PF do not show increased apoptotic cell death compared to wild-type discs.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    Co-expression of CG1583EP1516, with parkScer\UAS.T:Hsap\MYC, in the notum of the wing imaginal discs, under the regulation of Scer\GAL4ap-md544 suppresses the parkScer\UAS.T:Hsap\MYC phenotype of thoracic cleft formation resulting from abnormalities in JNK signalling during thorax closure.

    Co-expression of Traf2EP1516, with parkScer\UAS.T:Hsap\MYC, in the notum of the wing imaginal discs, under the regulation of Scer\GAL4ap-md544 suppresses the parkScer\UAS.T:Hsap\MYC phenotype of thoracic cleft formation resulting from abnormalities in JNK signalling during thorax closure.

    Coexpression of Traf2EP1516 with Traf1EP578, under the control of Scer\GAL4GMR.PF, does not alter the rough-eye phenotype caused

    by sole overexpression of Traf1EP578.

    Coexpression of Traf2EP1516 with either bskScer\UAS.cBa or hepScer\UAS.cBa, under the control of Scer\GAL4GMR.PF, does not affect the development of eyes.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer
    Comments
    Comments

    Overexpression of Traf2EP1516 under the control of Scer\GAL4hs.PB following a heat shock leads to an increase in Traf2 transcript levels.

    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (4)
    Reported As
    Symbol Synonym
    EP(X)DTRAF2
    Traf2EP1516
    UAS-Traf6EP1516
    Name Synonyms
    Secondary FlyBase IDs
      References (4)