FlyBase Allele Report: Dmel\dally[UAS.Tag:MYC]

FB2025_01 , released February 20, 2025

FB2025_01 , released February 20, 2025

Allele: Dmel\dally^UAS.Tag:MYC

General Information

Symbol

Dmel\dally^UAS.Tag:MYC

Species

D. melanogaster

Name

FlyBase ID

FBal0190518

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{UAS-dally.MYC}

Also Known As

UAS-Myc-dally

Key Links

Transgenic product class

(Takeo et al., 2005)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Takeo et al., 2005)

Mutagen

in vitro construct

(Takeo et al., 2005)

Progenitor genotype

Carried in construct

P{UAS-dally.MYC}

Cytology

Description

UASt regulatory sequences replace the Hsp70 promoter sequences.

(Takeo et al., 2005)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Tagged with

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of pupal stage, with Scer\GAL4^Act5C.PI

(Takeo et al., 2005)

partially lethal - majority die, with Scer\GAL4^29BD

(Takeo et al., 2005)

some die during pupal stage, with Scer\GAL4^29BD

(Takeo et al., 2005)

some die during pupal stage, with Scer\GAL4^Act5C.PI

(Takeo et al., 2005)

Phenotype Manifest In

leg, with Scer\GAL4^29BD

(Takeo et al., 2005)

posterior crossvein, with Scer\GAL4^71B

(Takeo et al., 2005)

posterior crossvein, with Scer\GAL4^en-e16E

(Takeo et al., 2005)

posterior crossvein, with Scer\GAL4^hh-Gal4

(Takeo et al., 2005)

posterior dorsocentral bristle | increased number, with Scer\GAL4^29BD

(Takeo et al., 2005)

posterior dorsocentral bristle | increased number, with Scer\GAL4^A9

(Takeo et al., 2005)

posterior dorsocentral bristle | increased number, with Scer\GAL4^dpp.blk1

(Takeo et al., 2005)

posterior dorsocentral bristle | increased number, with Scer\GAL4^en-e16E

(Takeo et al., 2005)

posterior dorsocentral bristle | increased number, with Scer\GAL4^hh-Gal4

(Takeo et al., 2005)

posterior dorsocentral bristle | increased number, with Scer\GAL4^ptc-559.1

(Takeo et al., 2005)

scutellar bristle | increased number, with Scer\GAL4^29BD

(Takeo et al., 2005)

scutellar bristle | increased number, with Scer\GAL4^A9

(Takeo et al., 2005)

scutellar bristle | increased number, with Scer\GAL4^dpp.blk1

(Takeo et al., 2005)

scutellar bristle | increased number, with Scer\GAL4^en-e16E

(Takeo et al., 2005)

scutellar bristle | increased number, with Scer\GAL4^hh-Gal4

(Takeo et al., 2005)

scutellar bristle | increased number, with Scer\GAL4^ptc-559.1

(Takeo et al., 2005)

wing, with Scer\GAL4^ptc-559.1

(Takeo et al., 2005)

wing margin, with Scer\GAL4^hh-Gal4

(Takeo et al., 2005)

wing vein, with Scer\GAL4^29BD

(Takeo et al., 2005)

wing vein, with Scer\GAL4^71B

(Takeo et al., 2005)

wing vein, with Scer\GAL4^A9

(Takeo et al., 2005)

Detailed Description

Statement

Reference

Ectopic expression of dally^{Scer\UAS.T:Hsap\MYC} induces the phenotypes in the wing, notum and legs shown below, depending on the Scer\GAL4 driver. The percentages of adult flies showing each phenotype is given. Expression with the ubiquitous Scer\GAL4^29BD driver causes: disordered wing veins - 66%, duplication of the dorsocentral and scutellar macrochaetae on the notum - 51%, malformed legs - 45%. Expression in the wing and haltere discs with Scer\GAL4^A9 causes: disordered wing veins - 99%, duplication of the dorsocentral and scutellar macrochaetae on the notum - 70%. Expression in the wing pouch with Scer\GAL4^71B causes: disordered wing veins - 97%, loss of the posterior crossvein - 83%. Expression along the anterior-posterior compartment boundary with Scer\GAL4^dpp.blk1 causes: duplication of the dorsocentral and scutellar macrochaetae on the notum - 40%. Expression along the anterior-posterior compartment boundary with Scer\GAL4^ptc-559.1 causes: folded wings - 21%, duplication of the dorsocentral and scutellar macrochaetae on the notum - 44%. Expression in the posterior compartment with Scer\GAL4^hh-Gal4 causes: loss of the posterior crossvein - 100%, notching of the wing margin - 80%, duplication of the dorsocentral and scutellar macrochaetae on the notum - 15%, malformed legs - 10%. Expression in the posterior compartment with Scer\GAL4^en-e16E causes: loss of the posterior crossvein - 32%, duplication of the dorsocentral and scutellar macrochaetae on the notum - 8%.

(Takeo et al., 2005)

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^A9/dally^UAS.Tag:MYC rescues dally^gem

(Takeo et al., 2005)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

dally^{Scer\UAS.T:Hsap\MYC}

dally^UAS.Tag:MYC

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections