Allele Dmel\nod^{NDD1-2.Scer\UAS.P\T.T:Avic\GFP-EGFP}

General Information
Symbol	Dmel\nod^{NDD1-2.Scer\UAS.P\T.T:Avic\GFP-EGFP}	Species	D. melanogaster
Name		FlyBase ID	FBal0190555
Feature type	allele	Associated gene	Dmel\nod

Allele class
Mutagen	in vitro construct - regulatory fusion, in vitro construct - coding region fusion, in vitro construct - amino acid replacement, in vitro construct - site directed mutagenesis
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - amino acid replacement (Cui and Hawley, 2005) in vitro construct - coding region fusion (Cui and Hawley, 2005) in vitro construct - regulatory fusion (Cui and Hawley, 2005) in vitro construct - site directed mutagenesis (Cui and Hawley, 2005)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: Amino acid replacement: G619A. Amino acid replacement: G621A. Scer\UAS regulatory and P\T promoter sequences drive expression of a mutated form of nod which is tagged at the C-terminal end with T:Avic\GFP^EGFP. (Cui and Hawley, 2005)
Carried in construct	P{UASp-nod-EGFP.NDD1-2} (Cui and Hawley, 2005)
Tagged with	T:Avic\GFP^EGFP (Cui and Hawley, 2005)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference Expression of nod^{NDD1-2.Scer\UAS.P\T.T:Avic\GFP-EGFP} under the control of Scer\GAL4^{nos.UTR.T:Hsim\VP16} in an In(1)FM7 nod⁺ background does not cause an increase in meiotic nondisjunction of the X and 4th chromosomes. (Cui and Hawley, 2005)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to rescue	Scer\GAL4^{nos.UTR.T:Hsim\VP16}/nod^{NDD1-2.Scer\UAS.P\T.T:Avic\GFP-EGFP} fails to rescue nod⁴/nod^a (Cui and Hawley, 2005)
Comments	Expression of nod^{NDD1-2.Scer\UAS.P\T.T:Avic\GFP-EGFP} under the control of Scer\GAL4^{nos.UTR.T:Hsim\VP16} fails to rescue the meiotic defects (high levels of X and 4th chromosome nondisjunction) seen in In(1)FM7 nod⁴/nod^a females. (Cui and Hawley, 2005)
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	nod^{NDD1-2.Scer\UAS.P\T.T:Avic\GFP-EGFP}
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Cui and Hawley, 2005, Genetics 171(4): 1823--1835 The HhH(2)/NDD domain of the Drosophila nod chromokinesin-like protein is required for binding to chromosomes in the oocyte nucleus. [FBrf0190714]

Allele Dmel\nodNDD1-2.Scer\UAS.P\T.T:Avic\GFP-EGFP

Allele Dmel\nod^{NDD1-2.Scer\UAS.P\T.T:Avic\GFP-EGFP}