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General Information
Symbol
Dmel\Socs36EΔSB.UASp
Species
D. melanogaster
Name
FlyBase ID
FBal0190996
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A C-terminal 60 amino acid residue deletion that removes the SOCS box.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Socs36EΔSB.Scer\UAS.P\T, under the control of Scer\GAL4c306, weakly inhibits border cell migration. Such egg chambers have an average of 4.9 border cells.

Expression of the Socs36EΔSB.Scer\UAS.P\T transgene under the control of Scer\GAL4en-e16E produces loss of the anterior cross vein with a 76% penetrance compared to the 99% penetrance observed when the Socs36E wild-type transgene is expressed. Scer\GAL4en-e16E>Socs36EΔSB.Scer\UAS.P\T expression also causes humeral outgrowth, but at a greatly reduced penetrance (17%) compared to that of the wild-type transgene (38%). The penetrance of the missing haltere phenotype is also reduced in flies expressing Socs36EΔSB.Scer\UAS.P\T.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of Socs36EΔSB.Scer\UAS.P\T suppresses the rough eye and extra R7 photoreceptor cell phenotype caused by expression of sevS11.T:Hsap\MYC under the control of Scer\GAL4hs.2sev.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Socs36EΔSB.Scer\UAS.P\T
Socs36EΔSB.UASp
Name Synonyms
Secondary FlyBase IDs
    References (3)