A C-terminal 60 amino acid residue deletion that removes the SOCS box.
anterior crossvein, with Scer\GAL4en-e16E
border follicle cell, with Scer\GAL4c306
haltere, with Scer\GAL4en-e16E
humerus, with Scer\GAL4en-e16E
Expression of Socs36EΔSB.Scer\UAS.P\T, under the control of Scer\GAL4c306, weakly inhibits border cell migration. Such egg chambers have an average of 4.9 border cells.
Expression of the Socs36EΔSB.Scer\UAS.P\T transgene under the control of Scer\GAL4en-e16E produces loss of the anterior cross vein with a 76% penetrance compared to the 99% penetrance observed when the Socs36E wild-type transgene is expressed. Scer\GAL4en-e16E>Socs36EΔSB.Scer\UAS.P\T expression also causes humeral outgrowth, but at a greatly reduced penetrance (17%) compared to that of the wild-type transgene (38%). The penetrance of the missing haltere phenotype is also reduced in flies expressing Socs36EΔSB.Scer\UAS.P\T.
Scer\GAL4hs.2sev/Socs36EΔSB.UASp is a suppressor of visible phenotype of Scer\GAL4hs.2sev, sevS11.Tag:MYC
Scer\GAL4hs.2sev/Socs36EΔSB.UASp is a suppressor of eye phenotype of Scer\GAL4hs.2sev, sevS11.Tag:MYC
Scer\GAL4hs.2sev/Socs36EΔSB.UASp is a suppressor | partially of photoreceptor cell R7 | increased number phenotype of Scer\GAL4hs.2sev, sevS11.Tag:MYC
Co-expression of Socs36EΔSB.Scer\UAS.P\T suppresses the rough eye and extra R7 photoreceptor cell phenotype caused by expression of sevS11.T:Hsap\MYC under the control of Scer\GAL4hs.2sev.